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US 12,178,789 B2Granted
Stress test and treatment of chronic kidney disease
AssigneeRenibus Therapeutics, Inc.
InventorsDonald Jeffrey Keyser, Alvaro F. Guillem, Bhupinder Singh, Richard A. Zager
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Abstract
The present invention involves a novel method for treatment of chronic kidney disease comprising administering a compound that induces a stress protein response in a patient, and administering a potent antioxidant if the patent's response is below a predefined level. It also involves a quantitative measure for determining a patient's antioxidant reserve capacity.
Claims7
A method comprising:
- (a) administering a compound to a patient, wherein the compound is a protoporphyrin or mesoporphyrin, which stimulates production of one or more antioxidant proteins in the patient;
- (b) obtaining one or more body fluid samples from a patient;
- and
- (c) measuring the level of the one or more anti-oxidant proteins produced in the patient.
1 more element
Dependencies are inferred from the claim text.