Methods, compositions, and devices for supplying dietary fatty acid needs
AssigneeAlcresta Therapeutics, Inc.
InventorsAlexey L. Margolin, Robert Gallotto, Bhami Shenoy
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Abstract
Nutritional formulas comprising long-chain polyunsaturated fatty acids (LC-PUFAs) are provided, along with methods and devices for preparing and/or administering nutritional formulas. In some embodiments, a percentage of the LC-PUFAs in the nutritional formula are in the form of monogiycerides and/or free fatty acids. In some embodiments, the nutritional formulas do not comprise added lipase. Also provided are methods for providing nutrition to a subject, methods for improving fat absorption, methods for improving cognitive ability, methods for preventing chronic lung disease, and methods for reducing the length of time a patient requires total parenteral nutrition.
Claims30
A device comprising:
- a container for receiving a nutritional composition;
- a first opening in the container, wherein the first opening is configured for connecting the container to a feeding tube;
- a second opening in the container;
- and
- a lipase immobilized within the container so that the nutritional composition is exposed to the lipase when the nutritional composition is received within the container,
- wherein the lipase is configured to hydrolyze fats within the nutritional composition to form a nutritional formula.
A method of providing a nutritional formula, the method comprising:
- flowing at least one of milk, infant formula, or enteral formula into the container of device 26;
- hydrolyzing fats in the at least one of milk, infant formula, or enteral formula to form the nutritional formula by exposing the milk, infant formula, or enteral formula to immobilized lipase contained within the container of the device;
- and
- outputting the nutritional formula from the device and into a feeding tube for ingestion by a subject.
Dependencies are inferred from the claim text.