# US 12,178,567 B2 · Medical analysis device for assessing a patient's suitability for anaesthesia > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,178,567 B2 - Document ID: US12178567B2 - Status: Granted - Kind: B2 - Application number: 16/972,846 - Filed: 2019-06-07 - Published: 2021-08-12 - Granted: 2024-12-31 - Earliest claimed: 2018-06-08 - Assignees: Technische UniversitäT Wien; Medizinische Universität Wien - Applicants: Technische Universität Wien; Medizinische Universität Wien - Inventors: Eugenijus Kaniusas; Klaus Ulrich Klein; Florian Thürk; Stefan Kampusch - Web page: https://patentgrep.com/patent/US12178567B2 ## CPC - A61B 5/0826: {Detecting or evaluating apnoea events (sleep apnoea A61B5/4818)} - A61B 5/02108: {from analysis of pulse wave characteristics} - A61B 5/02405: {Determining heart rate variability} - A61B 5/7292: {Prospective gating, i.e. predicting the occurrence of a physiological event for use as a synchronisation signal} - A61B 5/742: {using visual displays (displays for heart-related electrical signals, e.g. ECG, A61B5/339)} - A61B 5/7475: {User input or interface means, e.g. keyboard, pointing device, joystick} - G16H 40/63: for local operation - G16H 50/20: for computer-aided diagnosis, e.g. based on medical expert systems - G16H 50/30: for calculating health indices; for individual health risk assessment - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA ## Abstract The invention relates to a medical analysis device (1) for assessing a patient's suitability for anaesthesia by analysing at least one physiological biosignal (S) detected during an apnoea, wherein the medical analysis device (1) comprises the following: —an input interface (2) for detecting a time curve of at least one physiological biosignal (S) of a patient, —a computing unit (3) which is configured to compare a time curve of the at least one physiological biosignal (S) with at least one predefinable curve or a limit value according to an algorithm (4) in order to determine a patient's suitability for anaesthesia and to calculate an assessment result (E) depending thereon, wherein the time curve of the at least one physiological biosignal (S) comprises at least the duration of a patient's apnoea, and —an output interface (5) connected to the computing unit (3), to output the assessment result. ## Claims ### Claim 1 A medical analysis device (1) for assessing suitability for anaesthesia of a patient by analysing at least one physiological biosignal (S), the medical analysis device (1) comprising: one or more sensors (8) for detecting physiological biosignals (S) of the patient, wherein the physiological biosignals (S) include at least two of: arterial oxygen saturation, respiratory activity, heart rate variability, peripheral vasoconstriction, or arterial blood pressure, a computing unit (3) which is configured to: determine that at least two of the physiological biosignals (S) indicate that the patient is unfit for anaesthesia, and an output device (9) connected to the computing unit (3), to output an indication that the patient is unfit for anaesthesia. ### Claim 2 (depends on 1) The medical analysis device (1) according to claim 1, wherein the computing unit (3) is further configured to automatically detect an onset of apnoea and an end of apnoea by analysing a change over time of the respiratory activity. ### Claim 3 (depends on 1) The medical analysis device (1) according to claim 1, wherein the physiological biosignals (S) are recorded at least for a period of 180 seconds before an onset of a period of apnoea for the patient. ### Claim 4 (depends on 1) The medical analysis device (1) according to claim 1, wherein the physiological biosignals (S) are recorded at least for a period of 180 seconds after an end of the period of apnoea for the patient. ### Claim 5 (depends on 1) The medical analysis device (1) according to claim 1, wherein the computing unit (3) is assigned a non-transitory storage medium (6). ### Claim 6 (depends on 1) The medical analysis device (1) according to claim 1, wherein the output device (9) is a visual display and/or an acoustic display. ### Claim 7 (depends on 1) A system (7) comprising the medical analysis device (1) according to claim 1 and further comprising sensors (8) for detecting the physiological biosignals (S) of the patient. ### Claim 8 (depends on 1) A non-transitory storage medium (6) on which an algorithm (4) according to the medical analysis device (1) of claim 1 is stored. ### Claim 9 (depends on 1) The medical analysis device (1) according to claim 1, wherein the computing unit (3) determines that at least two of the physiological biosignals (S) indicate that the patient is not suitable for anaesthesia based on at least two of: the arterial oxygen saturation is greater than a desaturation threshold, the heart rate variability is less than a variability threshold, the peripheral vasoconstriction is less than a constriction threshold, or the arterial blood pressure regenerates at a time longer than a threshold time. ### Claim 10 (depends on 1) The medical analysis device (1) according to claim 1, wherein the computing unit (3) is further configured to: determine that the patient is unfit for anaesthesia based on at least two of the physiological biosignals (S) indicating that the patient is unfit for anaesthesia. ### Claim 11 A method for assessing suitability for anaesthesia of a patient, the method comprising: detecting, with one or more sensors (8), physiological biosignals (S) of a patient, wherein the physiological biosignals (S) include at least two of: arterial oxygen saturation, respiratory activity, heart rate variability, peripheral vasoconstriction, or arterial blood pressure, determining, using a computing unit (3), that at least two of the physiological biosignals (S) indicate that the patient is unfit for anaesthesia, and outputting, using an output device (9), an indication that the patient is unfit for anaesthesia. ### Claim 12 (depends on 11) The method of claim 11, further comprising: automatically detecting, using the computing unit (3), an onset of apnoea and an end of apnoea by analysing a change over time of the respiratory activity. ### Claim 13 (depends on 11) The method of claim 11, wherein the physiological biosignals (S) are recorded at least for a period of 180 seconds before an onset of a period of apnoea for the patient. ### Claim 14 (depends on 11) The method of claim 11, wherein the physiological biosignals (S) are recorded at least for a period of 180 seconds after an end of the period of apnoea for the patient. ### Claim 15 (depends on 11) The method of claim 11, wherein determining that at least two of the physiological biosignals (S) indicate that the patient is not suitable for anaesthesia comprises at least two of: the arterial oxygen saturation is greater than a desaturation threshold, the heart rate variability is less than a variability threshold, the peripheral vasoconstriction is less than a constriction threshold, or the arterial blood pressure regenerates at a time longer than a threshold time.