# US 12,178,562 B2 · Method for performing a magnetic resonance measurement of a patient, magnetic resonance apparatus, and computer program product

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- Number: US 12,178,562 B2
- Document ID: US12178562B2
- Status: Granted
- Kind: B2
- Application number: 17/697,890
- Filed: 2022-03-17
- Published: 2022-09-22
- Granted: 2024-12-31
- Earliest claimed: 2021-03-18
- Assignees: Siemens Healthineers AG
- Applicants: Siemens Healthcare GmbH
- Inventors: David Grodzki; Dieter Ritter
- Web page: https://patentgrep.com/patent/US12178562B2

## CPC

- A61B 5/055: involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
- G01R 33/5607: {by reducing the NMR signal of a particular spin species, e.g. of a chemical species for fat suppression, or of a moving spin species for black-blood imaging}
- A61B 5/1113: {Local tracking of patients, e.g. in a hospital or private home}
- G01R 33/543: {Control of the operation of the MR system, e.g. setting of acquisition parameters prior to or during MR data acquisition, dynamic shimming, use of one or more scout images for scan plane prescription (G01R33/546 takes precedence)}
- G01R 33/56509: {due to motion, displacement or flow, e.g. gradient moment nulling (G01R33/567 takes precedence)}
- G01R 33/56563: {caused by a distortion of the main magnetic field B0, e.g. temporal variation of the magnitude or spatial inhomogeneity of B0 (G01R33/56509, G01R33/56518, G01R33/56536 take precedence)}
- G01R 33/5673: {Gating or triggering based on a physiological signal other than an MR signal, e.g. ECG gating or motion monitoring using optical systems for monitoring the motion of a fiducial marker}
- G06T 7/0012: {Biomedical image inspection}
- A61B 5/1102: {Ballistocardiography}
- A61B 5/113: occurring during breathing
- A61B 5/7285: {for synchronizing or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal}
- A61B 2090/374: {NMR or MRI}
- G01R 33/243: {Spatial mapping of the polarizing magnetic field}
- G01R 33/5676: {Gating or triggering based on an MR signal, e.g. involving one or more navigator echoes for motion monitoring and correction}
- G06T 2207/10088: Magnetic resonance imaging [MRI]
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G01R: MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES (indicating correct tuning of resonant circuits H03J3/12)
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL

## Abstract

A method for performing a magnetic resonance measurement of a patient using a magnetic resonance apparatus is provided. The magnetic resonance apparatus includes a radiofrequency antenna unit for producing an excitation pulse. A first B0 field map for a first motion state of the patient, and a second B0 field map for a second motion state of the patient are provided. A first excitation pulse for the first motion state, and a second excitation pulse for the second motion state are determined based on the first B0 field map and the second B0 field map. A magnetic resonance measurement is performed, during which the motion state of the patient is monitored. When the patient is in the first motion state, the radiofrequency antenna unit transmits the first excitation pulse. When the patient is in the second motion state, the radiofrequency antenna unit transmits the second excitation pulse.

## Claims

### Claim 1

A method for performing a magnetic resonance measurement of a patient using a magnetic resonance apparatus, the magnetic resonance apparatus including a radiofrequency antenna unit for producing an excitation pulse, the method comprising:
providing a first B0 field map for a first motion state of the patient, and at least one further B0 field map for at least one further motion state of the patient;
determining a first excitation pulse for the first motion state and at least one further excitation pulse for the at least one further motion state based on the first B0 field map and the at least one further B0 field map; and
performing the magnetic resonance measurement, during which a motion state of the patient is monitored,
wherein the radiofrequency antenna unit transmits the first excitation pulse when the patient is in the first motion state,
wherein the radiofrequency antenna unit transmits the at least one further excitation pulse when the patient is in the at least one further motion state,
wherein the magnetic resonance apparatus further includes a gradient coil unit operable to produce magnetic field gradients, wherein a first gradient pulse for the first motion state and at least one further gradient pulse for the at least one further motion state are determined based on the first B0 field map and a second B0 field map, the at least one further gradient pulse being different than the first gradient pulse,
wherein the gradient coil unit applies the first gradient pulse when the patient is in the first motion state,
wherein the gradient coil unit applies the at least one further gradient pulse when the patient is in the at least one further motion state, and
wherein each of the first excitation pulse and the at least one further excitation pulse is a spectrally selective excitation pulse that is configured to achieve saturation of nuclear spins of a first bond type as the excitation to be achieved, such that flip angles of the first bond type and a second bond type are altered by different amounts.

### Claim 2 (depends on 1)

The method of claim 1, wherein the first B0 field map, the at least one further B0 field map, or the first B0 field map and the at least one further B0 field map are produced using acquired measurement data, simulation, or the acquired measurement data and the simulation.

### Claim 3 (depends on 1)

The method of claim 1, further comprising:
acquiring the first B0 field map at at least one first time instant, and the at least one further B0 field map at at least one further time instant,
wherein the patient is in the first motion state at the at least one first time instant, and the patient is in the at least one further motion state at the at least one further time instant.

### Claim 4 (depends on 1)

The method of claim 1, further comprising:
providing a first B1 field map for the first motion state of the patient, and at least one further B1 field map for at least one further motion state of the patient; and
determining the first excitation pulse and a second excitation pulse also based on the first B1 field map and the at least one further B1 field map.

### Claim 5 (depends on 1)

The method of claim 1, wherein the first excitation pulse and the at least one further excitation pulse are transmitted by parallel transmission using a plurality of transmit coils.

### Claim 6 (depends on 1)

The method of claim 1, wherein the first motion state and the at least one further motion state are cyclically recurring motion states.

### Claim 7 (depends on 6)

The method of claim 6, wherein the first motion state is an inspiration state, and
wherein the at least one further motion state is an expiration state.

### Claim 8 (depends on 1)

The method of claim 1, wherein the first motion state and the at least one further motion state are captured during acquisition of the first B0 field map, the at least one further B0 field map, or the first B0 field map and the at least one further B0 field map using a sensor unit, a sequence-based method, or the sensor unit and the sequence-based method.

### Claim 9 (depends on 1)

The method of claim 1, wherein acquisition of the first B0 field map, acquisition of the at least one further B0 field map, performance of the magnetic resonance measurement, or any combination thereof is controlled by motion gating, motion triggering, or motion gating and motion triggering.

### Claim 10 (depends on 9)

The method of claim 9, wherein the motion gating, the motion triggering, or the motion gating and the motion triggering are performed by a sensor unit, a sequence-based method, or the sensor unit and the sequence-based method.

### Claim 11 (depends on 1)

The method of claim 1, further comprising capturing a physiological parameter of the patient,
wherein the captured physiological parameter is taken into account in the determining of the first excitation pulse, the determining of the at least one further excitation pulse, or the determining of the first excitation pulse and the at least one further excitation pulse.

### Claim 12

A magnetic resonance apparatus that is configured to perform a magnetic resonance measurement of a patient, the magnetic resonance apparatus comprising:
a gradient coil unit operable to produce magnetic field gradients;
a radiofrequency antenna unit configured to produce an excitation pulse; and
a processor configured to:
provide a first B0 field map for a first motion state of the patient, and at least one further B0 field map for at least one further motion state of the patient;
determine a first excitation pulse for the first motion state and at least one further excitation pulse for the at least one further motion state based on the first B0 field map and the at least one further B0 field map; and
perform the magnetic resonance measurement, during which a motion state of the patient is monitored,
wherein the radiofrequency antenna unit is configured to transmit the first excitation pulse when the patient is in the first motion state,
wherein the radiofrequency antenna unit is configured to transmit the at least one further excitation pulse when the patient is in the at least one further motion state,
wherein the processor is further configured to determine a first gradient pulse for the first motion state and at least one further gradient pulse for the at least one further motion state based on the first B0 field map and a second B0 field map, the at least one further gradient pulse being different than the first gradient pulse,
wherein the gradient coil unit is configured to:
apply the first gradient pulse when the patient is in the first motion state; and
apply the at least one further gradient pulse when the patient is in the at least one further motion state, and
wherein each of the first excitation pulse and the at least one further excitation pulse is a spectrally selective excitation pulse that is configured to achieve saturation of nuclear spins of a first bond type as the excitation to be achieved, such that flip angles of the first bond type and a second bond type are altered by different amounts.

### Claim 13

In a non-transitory computer-readable storage medium that stores instructions executable by one or more processors to perform a magnetic resonance measurement of a patient using a magnetic resonance apparatus, the magnetic resonance apparatus including a radiofrequency antenna unit for producing an excitation pulse, the instructions comprising:
providing a first B0 field map for a first motion state of the patient, and at least one further B0 field map for at least one further motion state of the patient;
determining a first excitation pulse for the first motion state and at least one further excitation pulse for the at least one further motion state based on the first B0 field map and the at least one further B0 field map; and
performing the magnetic resonance measurement, during which a motion state of the patient is monitored,
wherein the radiofrequency antenna unit transmits the first excitation pulse when the patient is in the first motion state,
wherein the radiofrequency antenna unit transmits the at least one further excitation pulse when the patient is in the at least one further motion state,
wherein the magnetic resonance apparatus further includes a gradient coil unit operable to produce magnetic field gradients,
wherein a first gradient pulse for the first motion state and at least one further gradient pulse for the at least one further motion state are determined based on the first B0 field map and a second B0 field map, the at least one further gradient pulse being different than the first gradient pulse,
wherein the gradient coil unit applies the first gradient pulse when the patient is in the first motion state,
wherein the gradient coil unit applies the at least one further gradient pulse when the patient is in the at least one further motion state, and
wherein each of the first excitation pulse and the at least one further excitation pulse is a spectrally selective excitation pulse that is configured to achieve saturation of nuclear spins of a first bond type as the excitation to be achieved, such that flip angles of the first bond type and a second bond type are altered by different amounts.

### Claim 14 (depends on 13)

The non-transitory computer-readable storage medium of claim 13, wherein the first B0 field map, the at least one further B0 field map, or the first B0 field map and the at least one further B0 field map are produced using acquired measurement data, simulation, or the acquired measurement data and the simulation.

### Claim 15 (depends on 13)

The non-transitory computer-readable storage medium of claim 13, wherein the instructions further comprise:
acquiring the first B0 field map at at least one first time instant, and the at least one further B0 field map at at least one further time instant,
wherein the patient is in the first motion state at the at least one first time instant, and the patient is in the at least one further motion state at the at least one further time instant.

### Claim 16 (depends on 13)

The non-transitory computer-readable storage medium of claim 13, wherein the instructions further comprise:
providing a first B1 field map for the first motion state of the patient, and at least one further B1 field map for at least one further motion state of the patient; and
determining the first excitation pulse and a second excitation pulse also based on the first B1 field map and the at least one further B1 field map.
