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US 12,174,205 B2Granted
Phosphatidylethanolamine-specific probes
AssigneeNorthwestern University
InventorsSongwang Hou, Ming Zhao
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Abstract
Provided herein are phosphatidylethanolamine (PE)-specific probes and methods of use thereof. In particular, the present invention provides conjugates of PE binding moieties with detectable markers, and methods of use thereof to detect and/or characterize PE within cells.
Claims2
A composition comprising a conjugate of duramycin, a
- fluorescent protein and a nuclear localization signal,
- wherein the fluorescent protein is chemically or enzymatically tethered to a PEG or peptide linker which is also chemically or enzymatically tethered to the N-terminus of duramycin, or alternatively, the fluorescent protein and duramycin conjugate is a single protein unit produced recombinantly.
Dependencies are inferred from the claim text.