Closed bioprocessing device
AssigneeEMD Millipore Corporation
InventorsMichael James Susienka, Jeremy Perreault, Joseph Geringer, Brian Hillier, Joseph Muldoon, John Paul Amara
Life of this patent
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Abstract
A filtration module is provided, the module including at least one filtration packet containing filtration media or one or more membranes, such as a stack of membranes, the at least one filtration packet having one or more fluid ports, the one or more fluid ports being surrounded by a primary seal and a secondary seal spaced from the primary seal. The secondary seals are designed to maintain sterility of the assembly during shipping, handling and/or installation. A removable film may cover one or more fluid ports to maintain sterility prior to use.
Claims17
A filtration module comprising at least one filtration packet containing filtration media or one or more membranes, said at least one filtration packet having one or more fluid ports, said one or more fluid ports being surrounded by a primary seal and a secondary seal spaced from said primary seal, each of said primary seal and secondary seal configured to independent seal around said one or more fluid ports;
- said secondary seal extending outwardly from said one or more fluid ports a greater distance than said primary seal.
A plurality of filtration modules, each comprising one or more filtration packets containing filtration media or one or more membranes, wherein a first of said plurality of filtration modules comprises a first fluid port, said first fluid port being surrounded by a first primary seal and a first secondary seal spaced from said first primary seal and extending outwardly from said first fluid port a greater distance than said first primary seal;
- a second of said plurality of filtration modules comprises a second fluid port, said second fluid port being surrounded by a second primary seal and a second secondary seal spaced from said second primary seal and extending outwardly from said second fluid port a greater distance than said second primary seal;
- wherein when said first and second filtration modules are engaged under pressure such that said first fluid port aligns with said second fluid port, and said first secondary seal contacts said second secondary seal to prevent contaminant ingress into said first and second fluid ports.
An assembly, comprising a plurality of pre-assembled, pre-sterilized filtration modules, each of said pre-sterilized filtration modules comprising at least one filtration packet containing filtration media or one or more membranes, said at least one filtration packet having one or more fluid ports, said one or more fluid ports being surrounded by a primary seal and a secondary seal spaced from said primary seal;
- said secondary seal extending outwardly from said one or more fluid ports a greater distance than said primary seal.
A plurality of filtration modules, each comprising one or more filtration packets containing filtration media or one or more membranes, wherein a first of said plurality of filtration modules comprises a first fluid port;
- and a spacer plate being devoid of filtration media and having a second fluid port configured and positioned to align with said first fluid port of said first filtration module when in an assembled condition;
- said second fluid port of the spacer plate having a gasket positioned concentrically to said second fluid port;
- wherein when said plurality of filtration modules and said spacer plate are engaged under pressure such that said first fluid port aligns with said second fluid port, said concentric gasket prevents contaminant ingress into said first fluid port.
Dependencies are inferred from the claim text.