Organic gel or liquid chromatography method
OwnerFrancois Parmentierinventor
Life of this patent
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Abstract
A chromatography method in which a gaseous, liquid or supercritical mobile phase containing species to be separated is circulated through a packing. The packing includes a plurality of capillary ducts extending in the packing between an upstream face through which the mobile phase enters the packing and a downstream face through which the mobile phase leaves the packing. A continuous medium permeable to molecular diffusion extends between the ducts, including a porous organic gel or an organic liquid with at least one network of connected pores, the size of which is greater than two times the molecular diameter of at least one species to be separated. The at least one species has a diffusive path between the ducts.
Claims14
A packing for chromatography, comprising:
- a monolith of porous organic gel including at least one network of connected pores, and
- a plurality of capillary conduits crossing the monolith between an upstream face configured for inflowing of a mobile phase into the packing and a downstream face configured for an outflow of the mobile phase from the packing,
- the monolith thereby forming a continuous medium permeable to molecular diffusion extending between said conduits.
A packing for chromatography, comprising:
- a plurality of capillary conduits crossing the packing between an upstream face configured for inflowing of a mobile phase into the packing and a downstream face configured for an outflow of the mobile phase from the packing, and
- a continuous medium permeable to molecular diffusion extending between said conduits, including a network of connected pores and a porous organic liquid extending in the connected pores.
A packing for chromatography, comprising:
- a monolith of a chemically inert porous material having a continuous network of pores,
- a plurality of capillary conduits crossing the monolith between an upstream face configured for inflowing of a mobile phase into the packing and a downstream face configured for an outflow of the mobile phase from the packing, and
- a porous organic gel permeable to molecular diffusion filling the pores of the monolith, the organic gel thereby forming a continuous medium permeable to molecular diffusion extending between the conduits.
A packing for chromatography, comprising:
- a monolith of a chemically inert porous material having a continuous network of pores,
- a plurality of capillary conduits crossing the monolith between an upstream face configured for inflowing of a mobile phase into the packing and a downstream face configured for an outflow of the mobile phase from the packing, and
- a porous organic gel permeable to molecular diffusion covering an inner surface of the capillary conduits over a selected thickness so as to retain, in the network of pores of the monolith, a free space for diffusion of the mobile phase, said organic gel thereby forming a continuous network of pores between the conduits which defines a continuous medium permeable to molecular diffusion extending between the conduits.
Dependencies are inferred from the claim text.