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US 12,171,814 B2Granted
Protein complex including botulinum toxin translocation domain and endolysin and antibacterial composition including same
AssigneeMvrix Co., Ltd.
InventorsDae Hyuk Kweon, Wonbeom Park, Jihwan Chun
Life of this patent
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Abstract
Provided is a protein complex including a botulinum toxin translocation domain and endolysin. When used, the protein complex including a botulinum translocation domain and endolysin according to the present invention exhibits an antibacterial effect and thus can be used as an antibacterial composition or an antibiotic.
Claims5
An antibacterial composition comprising a protein complex comprising a botulinum toxin translocation domain and endolysin,
- wherein the botulinum toxin translocation domain comprises at least one amino acid sequence selected from the group consisting of SEQ ID NOS:
- 29, 38 and 39, and
- wherein the endolysin comprises at least one selected from the group consisting of lys, LysPA26, PB1_gp48, LysAB2_P3, PlyF307, AcLys, PlyPA03, PlyPA91, Abtn-4, WCHABP1_gp01, WCHABP12_gp19, gh-1p12, B3ORF25, phi-13Sp4, phi-6S_4, KP27_166, KP13_gp066, BI057_gp221, LPSE_00024, STP4a_120, Lys68, SPN1S_0028 and P22gp66.
Dependencies are inferred from the claim text.