Peak determination in two-dimensional optical spectra
AssigneeThermo Fisher Scientific (Bremen) GmbH
InventorsHans-Juergen Schlueter, Antonella Guzzonato, Norbert Quaas, Peter Huelstede
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Abstract
A method of determining a peak intensity in an optical spectrum is described. The method includes producing a two-dimensional array of spectrum values by imaging the optical spectrum onto a detector array. An offset using an actual location and an expected location of a peak of an interpolated subarray is used to adjust an expected location of another peak that is within another two-dimensional subarray. Interpolated spectrum values are then used to produce a peak intensity value of the second peak.
Claims23
A method of determining a peak intensity in an optical spectrum, the method comprising:
- producing a two-dimensional array of spectrum values by imaging the optical spectrum onto a detector array,
- selecting a first two-dimensional subarray of the array of spectrum values such that the subarray includes a first peak of the spectrum, the first peak having an expected location,
- interpolating the spectrum values of the first two-dimensional subarray in two dimensions to produce a first interpolated subarray,
- determining, by using the first interpolated subarray, an actual location of the first peak,
- determining an offset by using the actual location and the expected location of the first peak,
- adjusting an expected location of a second peak of the spectrum by using the offset,
- selecting a second two-dimensional subarray of the array of spectrum values such that the second subarray includes the second peak, the second peak having an adjusted expected location, and
- using, within the second subarray, interpolated spectrum values to produce a peak intensity value of the second peak.
A method of determining offset in optical spectroscopy, the method comprising:
- detecting a two-dimensional optical spectrum by using a detector array,
- defining a two-dimensional subarray of the detector array, which subarray includes an expected location of a peak of the spectrum,
- interpolating the spectrum of the two-dimensional subarray in two dimensions to produce an interpolated partial two-dimensional spectrum,
- determining, by using the interpolated partial two-dimensional spectrum, the actual location of the peak, and
- determining an offset by using the actual location and the expected location of the peak.
A computer program product including one or more non-transitory computer-readable media having computer programs instructed stored therein, the computer program instructions being configured such that, when executed by one or more computing devices, the computer program instructions cause the one or more computing devices to:
- produce a two-dimensional array of spectrum values by imaging the optical spectrum onto a detector array;
- select a first two-dimensional subarray of the array of spectrum values such that the subarray includes a first peak of the spectrum, the first peak having an expected location;
- interpolate the spectrum values of the first two-dimensional subarray in two dimensions to produce a first interpolated subarray;
- determine, by using the first interpolated subarray, an actual location of the first peak;
- determine an offset by using the actual location and the expected location of the first peak;
- adjust an expected location of a second peak of the spectrum by using the offset;
- select a second two-dimensional subarray of the array of spectrum values such that the second subarray includes the second peak, the second peak having an adjusted expected location;
- and
- use, within the second subarray, interpolated spectrum values to produce a peak intensity value of the second peak.
A system for optical spectrometry, the system comprising:
- a detector array;
- and
- a processor with an associated memory, wherein the processor is configured to execute instructions in the associated memory to:
- produce a two-dimensional array of spectrum values by imaging the optical spectrum onto a detector array;
- select a first two-dimensional subarray of the array of spectrum values such that the subarray includes a first peak of the spectrum, the first peak having an expected location;
- interpolate the spectrum values of the first two-dimensional subarray in two dimensions to produce a first interpolated subarray;
- determine, by using the first interpolated subarray, an actual location of the first peak;
- determine an offset by using the actual location and the expected location of the first peak;
- adjust an expected location of a second peak of the spectrum by using the offset;
- select a second two-dimensional subarray of the array of spectrum values such that the second subarray includes the second peak, the second peak having an adjusted expected location;
- and
- use, within the second subarray, interpolated spectrum values to produce a peak intensity value of the second peak.
Dependencies are inferred from the claim text.