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AssigneeTaiwanj Pharmaceuticals Co., Ltd.
InventorsSyaulan S. Yang, Yan-feng Jiang, Meng-hsien Liu, Chia-hao Chang, Hao Shiuan Liu, Ying-chu Shih, Sheng Hung Liu, Chiung Wen Wang, Ting-ni Huang
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The compounds represented by Formula (I), which are peripheral alkyl and alkenyl chains extended benzene derivatives, are useful as dual autotaxin (ATX)/histone deacetylase (HD AC) inhibitors. These compounds may be included in a pharmaceutical composition along with a pharmaceutically acceptable carrier, and be used in a therapeutically effective amount for prophylaxis or treatment of various diseases and disorders.
A compound selected from the group consisting of the compounds delineated in Table A or a geometric isomer, enantiomer, diastereomer, racemate, pharmaceutically acceptable salt or solvate thereof:
Dependencies are inferred from the claim text.