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US 12,162,818 B2Granted
Inhibitors of the n-terminal domain of the androgen receptor
AssigneesThe Regents of the University of California, The United States Government as represented by the Department of Veterans Affairs
InventorsMatthew Rettig, Michael E. Jung, D. Elshan Nakath G. Ralalage, Jiabin An
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Abstract
The present disclosure provides compounds of Formula (VIIb) and methods for inhibiting or degrading the N-terminal domain of the androgen receptor, as well as methods for treating cancers such as prostate cancer.
Claims15
A compound represented by formula VIIb or a pharmaceutically acceptable salt thereof:
- wherein:
- each R8 is independently selected from halo, alkyl, or alkyloxy;
- each R9 is independently selected from halo, alkyl, or alkyloxy;
- t is 1 or 2;
- and
- q is 1 or 2.
3 more elements
Dependencies are inferred from the claim text.