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US 12,161,829 B2Granted
Device positionable in the uterine cavity and method of treatment thereof
AssigneeOCON Medical Ltd.
InventorsIlan Baram, Eran Nir
Life of this patent
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Abstract
A delivery vehicle for a silver ion source such as silver nitrate and the like, suitable for use in the treatment of menorrhagia, comprises a plurality of beads bearing a tissue cauterizing amount of a silver ion source. In some embodiments, the silver ion source is silver nitrate, in combination with a binder of hydroxy propyl cellulose and a diluent of potassium nitrate. In some embodiments, the plurality of beads is useful in treating menorrhagia of a mammalian uterus. Silver ions are delivered in a sufficient amount to the endometrium to cause necrosis of the endometrial tissue.
Claims14
An intrauterine device comprising:
- a wire having a portion capable of forming an elastically deformable three-dimensional structure;
- wherein the three-dimensional structure:
- a) is elastically deformable to a partially collapsed configuration;
- b) has a crush force of at least 15 grams/cm2;
- and
- c) is configured to elastically contract and expand in response to contraction and expansion of the uterine cavity,
- a plurality of beads, comprising:
- 80% to 98% by weight of formulated active materials,
- wherein the formulated active materials comprise 75% to 100%
- by weight of silver nitrate and 0% to 25% by weight of potassium nitrate,
- wherein the ratio of potassium nitrate to silver nitrate is from 1:19 to 1:3, and
- 2% to 20% by weight of a hydroxy propyl cellulose binder;
- and
- two fixing beads, each positioned at opposite ends of the wire.
11 more elements
Dependencies are inferred from the claim text.