Vaccines for Neisseria gonorrhoeae

A method of immunizing a human subject against Neisseria gonorrhoeae by administering to the subject a single dose or multiple doses of an immunogenic composition comprising an immunologically effective amount of a purified Neisserial Heparin Binding Antigen (NHBA) of Neisseria meningitidis comprising the amino acid sequence of SEQ ID NO:

• 8;
• wherein the human subject has been immunized against N. meningitidis during childhood;
• wherein the human subject who is immunized with the single dose or the multiple doses of the immunogenic composition is an adult at increased risk of infection with N. gonorrhoeae relative to the average risk in the general population;
• and
• wherein the immunogenic composition immunizes the human subject against infection or disease caused by N. gonorrhoeae.