Microbiome-based diagnosis, prediction and treatment of relapsing obesity
AssigneeYeda Research and Development Co. Ltd.
InventorsEran Elinav, Eran Segal
Life of this patent
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Abstract
A method of analyzing the likelihood of weight regain in a subject who has reached a target weight by practicing a weight loss program is disclosed. The method comprises determining an amount or presence of at least one microbe and/or product thereof in the gut microbiome of the subject, wherein the amount of the at least one microbe is altered during a prior weight gain period of the subject to reach a level representative of an obese subject and further wherein the amount of the at least one microbe is retained at the level following the weight loss program, wherein the amount or presence of the at least one microbe or product thereof is predictive of weight regain.
Claims7
A method of reducing the risk of weight gain in a subject who has completed a weight loss program and reached a target weight, the method comprising administering to the subject a fecal transplant of a donor subject who has not undergone a weight loss program, wherein said donor subject has a BMI between 18.5-24.9, thereby reducing the risk of weight gain in the subject.
Dependencies are inferred from the claim text.