Back to results
US 12,157,903 B2Granted
Compositions and methods for reducing progression of nephrolithiasis
AssigneeYale University
InventorsDemetrios Braddock, Clemens Bergwitz
Life of this patent
Estimating the term…
Abstract
The present invention includes compositions and methods for treating and/or preventing renal and/or kidney stones in a human subject. In certain embodiments, the subject is administered certain ENPP1 polypeptides or ENPP3 polypeptides, mutants, or mutant fragments thereof.
Claims9
A method of reducing progression of nephrolithiasis in a subject diagnosed with nephrolithiasis,
- the method comprising administering a therapeutically effective amount of a soluble EctoNucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) polypeptide to the subject, wherein progression of the nephrolithiasis is reduced in the subject.
Dependencies are inferred from the claim text.