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AssigneeSK Innovation Co., Ltd.
InventorsJae Yeon Park, Ki Sung Lee, Tae Young Lee
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Disclosed are a recombinant acid-resistant yeast having lactic acid-producing ability and suppressed glycerol production and a method of preparing lactic acid using the same. More particularly, disclosed are a recombinant acid-resistant yeast into which a gene involved in lactic acid production is introduced and in which a gene involved in glycerol production is deleted or attenuated, and a method of preparing lactic acid using the same. When producing lactic acid using the recombinant acid-resistant yeast, the production of lactic acid is maintained while the production of glycerol is reduced, so crosslinking by glycerol can be suppressed in the oligomerization reaction for conversion to lactide, and thus the conversion yield of lactic acid to lactide can be increased.
A recombinant strain having lactic acid-producing ability, wherein the recombinant strain having lactic acid-producing ability is a YBC strain deposited as KCTC13508BP further modified to comprise an introduced gene encoding lactate dehydrogenase and to comprise a deletion or attenuation of a gene encoding an enzyme that converts dihydroxyacetone phosphate to glycerol-3-phosphate.
A recombinant strain having lactic acid-producing ability, wherein the recombinant strain having lactic acid-producing ability is a YBC strain deposited as KCTC13508BP further modified to comprise an introduced gene encoding lactate dehydrogenase and deletions of:
Dependencies are inferred from the claim text.