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US 12,154,773 B2Granted
Systems and methods for collision induced dissociation of ions in an ion trap
AssigneePurdue Research Foundation
InventorsRobert Graham Cooks, Dalton Snyder
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Abstract
The invention generally relates to systems and methods for collision induced dissociation of ions in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central processing unit (CPU). The CPU includes storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to generate one or more signals, and apply the one or more signals to the ion trap in a manner that all ions within the ion trap are fragmented at a same Mathieu q value.
Claims6
A mass spectrometry system comprising:
- a mass spectrometer comprising an ion trap;
- and
- a central processing unit (CPU), and storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to:
- generate a radio frequency (RF) signal comprising an amplitude;
- and
- apply the RF signal to ions in the ion trap in a manner that after an injection and cooling period, the RF signal is increased and then a fixed frequency resonance excitation waveform is applied in presence of the RF signal for fragmenting the ions and the amplitude of the RF signal is then ramped in a reverse direction from high amplitude to low amplitude.
3 more elements
Dependencies are inferred from the claim text.