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US 12,139,519 B2Granted
CRY2 variant having increased photosensitivity and use thereof
AssigneeInstitute for Basic Science
InventorsWondo Heo, Sungsoo Kim, Sang Kyu Lee, Taeyoon Kyung
Life of this patent
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Abstract
Provided is a CRY2 variant in which E279 and/or E281 having a negative charge in a N277SEGE281 sequence of SEQ ID NO: 1 is substituted with any one selected from the neutral amino acid group of alanine (A), isoleucine (I), leucine (L), valine (V), phenylalanine (F), methionine (M) and tryptophan (W), or in which S278 or G280 of a N277SEGE281 sequence of SEQ ID NO: 1 is substituted with any one selected from the bulky amino acid group of tryptophan (W) and phenylalanine (F).
Claims14
A CRY2 variant in which
- at least one of E279 and E281 having a negative charge among a N277SEGE281 sequence of SEQ ID NO:
- 1 is substituted with any one selected from the neutral amino acid group of alanine (A), isoleucine (I), leucine (L), valine (V), phenylalanine (F), methionine (M), and tryptophan (W), or
- S278 or G280 in the N277SEGE281 sequence of SEQ ID NO:
- 1 is substituted with any one selected from a bulky amino acid group of tryptophan (W) and phenylalanine (F).
1 more element
Dependencies are inferred from the claim text.