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US 12,139,503 B2Granted
Borylated amino acid compositions for use in boron neutron capture therapy and methods thereof
AssigneeTAE Life Sciences, LLC
InventorsMichael Y. Torgov, Tioga J. Martin, Arthur B. Raitano
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Abstract
Borylated Amino Acid (“BAA”) compositions and methods of making BAAs are disclosed herein. Consequently, the BAAs can be administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders and other disease by utilizing a Neutron Capture Therapy modality.
Claims11
A method of delivering a borylated amino acid composition to a cell for treating a disease, the method comprising:
- (i) administering to a patient a Dosage Unit Form composition comprising a chemical structure as follow:
- (ii) allowing the Dosage Unit Form composition to accumulate in the cell;
- and
- (iii) irradiating the cell with neutrons.
1 more element
The method of clam 1, wherein the treatment is Proton Boron Fusion Therapy (PBFT).
A composition comprising a chemical structure as follows:
Dependencies are inferred from the claim text.