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US 12,138,629 B2Granted
Microfluidic device and a method for provision of double emulsion droplets
AssigneeSamplix Aps
InventorsThomas Kvist, Esben Bjørn Madsen, Solène Cherre, Marie Just Mikkelsen
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Abstract
A microfluidic device, a method for manufacturing a microfluidic device, and a method for provision of double emulsion droplets using a microfluidic device. Furthermore, an assembly configured to supply pressure to the microfluidic device for provision of double emulsion droplets. Furthermore, a kit comprising a plurality of microfluidic devices and a plurality of fluids configured for use with the microfluidic device for provision of double emulsion droplets.
Claims17
A microfluidic device comprising:
- a microfluidic section comprising a plurality of microfluidic units;
- and
- a container section comprising a plurality of groups of containers comprising one group of containers for each microfluidic unit;
- wherein each microfluidic unit comprises a fluid conduit network comprising:
- a plurality of supply conduits comprising a primary supply conduit, a secondary supply conduit, and a tertiary supply conduit;
- a transfer conduit comprising a first transfer conduit part having a first affinity for water;
- a collection conduit comprising a first collection conduit part having a second affinity for water being different from the first affinity for water;
- a first fluid junction providing fluid communication between the primary supply conduit, the secondary supply conduit, and the transfer conduit;
- and
- a second fluid junction providing fluid communication between the tertiary supply conduit, the transfer conduit, and the collection conduit;
- wherein each fluid conduit network is formed in part by a first component and in part by a second component, and wherein the first component comprises a first substrate having a first coated zone and a first non-coated zone, and wherein the second component comprises a second substrate having a second coated zone and a second non-coated zone, and wherein, for each fluid conduit network, one of the first transfer conduit part and the first collection conduit part is formed in part by a primary part of the first coated zone and in part by a primary part of the second coated zone, and wherein the other of the first transfer conduit part and the first collection conduit part is formed in part by a primary part of the first non-coated zone and in part by a primary part of the second non-coated zone;
- wherein each first transfer conduit part extends from the corresponding first fluid junction, and wherein each first collection conduit part extends from the corresponding second fluid junction, and wherein each group of containers comprises a plurality of containers comprising a collection container and a plurality of supply containers comprising a primary supply container, a secondary supply container, and a tertiary supply container, wherein for each group of containers:
- the collection container is in fluid communication with the collection conduit of the corresponding microfluidic unit;
- the primary supply container is in fluid communication with the primary supply conduit of the corresponding microfluidic unit;
- the secondary supply container is in fluid communication with the secondary supply conduit of the corresponding microfluidic unit;
- and
- the tertiary supply container is in fluid communication with the tertiary supply conduit of the corresponding microfluidic unit.
14 more elements
Dependencies are inferred from the claim text.