Composition of polymer gel dosimeters for radiation therapy

A process of making a three-dimensional dosimeter gel, comprising;

• fabricating the three-dimensional dosimeter gel under a fume hood in normal atmospheric conditions.;
• adding a gelatin Type B an ultra-pure de-ionized water and left for 10 minutes to soak before heating up to 50° C. for 1 hour;
• cooling down to 45° C., and adding BIS, monomer and ethylene glycol respectively and kept stirring until completely dissolved;
• after the solution cooled down to 35° C., THPC was added as antioxidant;
• the final polymer gels were filled into NMR tubes and sealed;
• and
• all gels were stored in a refrigerator (10° C.) overnight prior to irradiation.

A three-dimensional dosimeter gel, comprising;

• a) a N, N′-methylene-bis-acrylamide (BIS) cross-linker wt % from 1 to 4%;
• b) a Gelatin Type B wt % from 1 to 10%;
• c) a Tetrakis (hydroxymethyl) phosphonium chloride (THPC) from 5-20 mM;
• d) an Ethylene glycol wt % from 1 to 50%;
• e) a De-ionized water as a solvent;
• and
• f) a monomer in a specific range, wherein the monomer is a N-Vinylcaprolactam (NVCL) monomer and in the specific range from 2 to 10% wt %.