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US 12,138,374 B2Granted
Devices and methods to infuse gases into and out of blood
OwnerDemetris Yannopoulos, Robert F. Wilsoninventors
Life of this patent
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Abstract
Gaseous nanobubbles are created and infused into the blood stream to therapeutic effect such as oxygenation. The nanobubbles may be created inside or outside of the patient, either during infusion or prior to infusion. CO2 is extracted from the blood to improve oxygen.
Claims11
A method of infusing blood with a gas comprising:
- creating, in vivo, bubbles of gas in blood of a patient when that blood is contained within a catheter;
- reducing said bubbles to nanobubbles within the catheter, said nanobubbles having diameters of less than 500 nm;
- introducing the blood of the patient containing said nanobubbles into a bloodstream of the patient;
- and,
- rupturing said nanobubbles using external energy at a target location.
2 more elements
A system for infusing blood with a gas comprising:
- a gas source;
- a liquid medium comprising blood;
- a gas infuser connected to said gas source and located in said liquid medium that creates gas bubbles when gas from said gas source flows through said gas infuser;
- an ensonifier located in said liquid medium and connected to a power source wherein when energized said ensonifier reduces said gas bubbles to nanobubbles, said nanobubbles having a diameter of less than 500 nm;
- and,
- a catheter useable to deliver said nanobubbles in said liquid medium to a bloodstream of a patient from a portion of the catheter sized and shaped for in vivo placement within a blood vessel of the patient, wherein the portion includes the gas infuser and the ensonifier, and wherein the portion is defined by an opening in the catheter that receives blood from the bloodstream and an opening in the catheter that directs blood into the bloodstream.
3 more elements
Dependencies are inferred from the claim text.