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US 12,138,319 B2Granted
Chimeric protein and related genic transfer technology
AssigneesLucio Pastore, Eleonora Leggiero
InventorsLucio Pastore, Eleonora Leggiero
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Abstract
A human chimeric protein(1) is described, expressed by a viral vector (2) designed for treating patients affected by genetic disorders, composed of a first cDNA sequence [SEQ. 2] of a N-terminal extracellular portion of a human receptor (4) of low-density lipoproteins (5) (hLDLR), fused with a second cDNA sequence [SEQ. 3] of the human transferrin (7) (hTf).
Claims7
A viral vector encoding a chimeric protein comprising a first cDNA sequence of SEQ ID:
- 2 encoding a portion of a human low-density lipoprotein receptor fused to a second cDNA sequence of SEQ ID:
- 3 encoding a human transferrin.
Dependencies are inferred from the claim text.