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US 12,138,298 B2Granted
Expression vector for cholesterol 24-hydrolase in therapy of polyglutamine repeat spinocerebellar ataxias
AssigneesBrainvectis, Inserm (Institut National De La SantéEt De La Recherche MéDicale), Universidade De Coimbra, Centro De NeurociêNcias Biologia Celular
InventorsSandro Alves, Nathalie Cartier-Lacave, Luis Pereira De Almeida, Clévio Nobrega, Liliana Mendonça
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Abstract
The present invention relates to a vector for use in the treatment of a polyglutamine repeat spinocerebellar ataxia, which vector comprises cholesterol 24-hydroxylase encoding nucleic acid.
Claims14
A method of treatment of a Polyglutamine repeat spinocerebellar ataxia, comprising administering a vector which comprises cholesterol 24-hydroxylase encoding nucleic acid to a patient in need thereof.
Dependencies are inferred from the claim text.