Extraction and purification of cannabinoids
AssigneeM-For, LLC
InventorZachary White
Life of this patent
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Abstract
An improved method for making cannabigerol (CBG) utilizing the following steps. CBG-containing material is contacted with an aqueous alkaline solution containing a hydroxide base and essentially no organic solvents, thereby extracting cannabinoids including carboxylic acids and salts and producing an alkaline extract. Non-soluble CBG-containing material is removed from the alkaline extract to produce a clarified alkaline extract. The extracted cannabinoids are decarboxylated and the resulting cannabigerol is crystallized/precipitated from the clarified alkaline extract at a pH greater than 7.
Claims13
A method for purifying cannabigerol from cannabis, the method comprising:
- a. contacting cannabis with an aqueous alkaline solution of a strong inorganic base selected from the group consisting of NaOH, KOH, NH4OH, and combinations thereof, to extract cannabigerolic acid from the cannabis and produce an aqueous alkaline extract of cannabis, wherein no organic solvents are used;
- b. purging the aqueous alkaline extract of cannabis with an inert gas selected from the group consisting of nitrogen, argon, helium, and combinations thereof to produce a purged aqueous alkaline extract of cannabis;
- c. removing non-soluble material from the purged aqueous alkaline extract of cannabis via extraction or centrifugation to produce a clarified extract of cannabis;
- d. decarboxylating the clarified extract of cannabis at a temperature sufficient to convert the cannabigerolic acid to cannabigerol;
- e. crystallizing and precipitating the cannabigerol from the clarified extract at a pH greater than 7 to produce crystallized and precipitated cannabigerol;
- f. filtering the crystallized and precipitated cannabigerol to produce 85% to 100% cannabigerol and a barren aqueous solution of the strong inorganic base;
- and
- g. recycling and reusing the barren aqueous solution of the strong inorganic base from step (f) and then extracting new cannabis with the barren aqueous solution of a strong inorganic base selected from the group consisting of NaOH, KOH, NH4OH, and combinations thereof.
Dependencies are inferred from the claim text.