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US 12,138,140 B2Granted
Wound covering for wound monitoring and therapeutic agent delivery
AssigneeUVic Industry Partnerships Inc.
InventorsMohsen Akbari, Bahram Mirani, Aziz Ghahary, Mohammad A. Siddiqui
Life of this patent
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Abstract
A wound covering includes a flexible main body, and a sensor element incorporated into the main body. The sensor element includes a mesh formed from a plurality of fibers, and the sensor element is configured to undergo a change in appearance in response to a change in a parameter associated with wound exudate. The wound covering further includes a supply of therapeutic agent configured to diffuse the therapeutic agent from the wound covering into a wound when the wound covering is placed on the wound.
Claims17
A wound covering, comprising:
- a flexible main body;
- a sensor element incorporated into the main body, the sensor element comprising a mesh formed from a plurality of fibers, the sensor element being configured to undergo a detectable change in appearance in response to a change in a parameter associated with wound exudate, wherein the fibers comprise a plurality of sensor particles and a hydrogel, the sensor particles comprising
- one or more indicator compounds configured to undergo the detectable change in appearance in response to the change in the parameter associated with the wound exudate, and
- beads comprising an ion-exchange resin or a hydrogel;
- and
- a supply of therapeutic agent configured to diffuse the therapeutic agent from the wound covering into a wound when the wound covering is placed on the wound.
3 more elements
A wound covering, comprising:
- a flexible main body including at least
- a first layer comprising a hydrogel;
- and
- a second layer disposed on the first layer, the second layer comprising a porous hydrophobic material;
- a sensor element incorporated into the main body and at least partially incorporated into the first layer, the sensor element comprising a mesh formed from a plurality of fibers, the sensor element being configured to undergo a change in appearance in response to a change in a parameter associated with wound exudate;
- and
- a supply of therapeutic agent configured to diffuse the therapeutic agent from the wound covering into a wound when the wound covering is placed on the wound.
4 more elements
A wound covering, comprising:
- a flexible main body;
- a sensor element incorporated into the main body, the sensor element comprising a mesh formed from a plurality of fibers, the sensor element being configured to undergo a change in appearance in response to a change in a parameter associated with wound exudate;
- a supply of therapeutic agent configured to diffuse the therapeutic agent from the wound covering into a wound when the wound covering is placed on the wound;
- and
- a therapeutic agent delivery element including a mesh formed from a plurality of fibers, the plurality of fibers of the mesh of the therapeutic agent delivery element comprising a hydrogel, wherein
- the therapeutic agent is incorporated into the hydrogel.
3 more elements
A wound covering, comprising:
- a flexible main body;
- a sensor element incorporated into the main body, the sensor element comprising a mesh formed from a plurality of fibers, the sensor element being configured to undergo a change in appearance in response to a change in a parameter associated with wound exudate;
- a supply of therapeutic agent configured to diffuse the therapeutic agent from the wound covering into a wound when the wound covering is placed on the wound;
- and
- a therapeutic agent delivery element including a mesh formed from a plurality of fibers, the plurality of fibers of the mesh of the therapeutic agent delivery element comprising a plurality of porous hydrogel particles, the porous hydrogel particles comprising the therapeutic agent, and
- the porous hydrogel particles are configured to release the therapeutic agent when the parameter exceeds a predetermined threshold.
3 more elements
A wound covering, comprising:
- a flexible main body;
- a sensor element incorporated into the main body, the sensor element comprising a mesh formed from a plurality of fibers, the sensor element being configured to undergo a change in appearance in response to a change in a parameter associated with wound exudate;
- a supply of therapeutic agent configured to diffuse the therapeutic agent from the wound covering into a wound when the wound covering is placed on the wound;
- and
- a humidity sensor element incorporated into the main body, the humidity sensor element comprising a substrate having a coating configured to undergo a change in appearance in response to a change in humidity.
2 more elements
A wound covering, comprising:
- a flexible main body;
- a sensor element having a first region, a second region, a third region, and a fourth region incorporated into the main body, the sensor element comprising a mesh formed from a plurality of fibers, the sensor element being configured to undergo a change in appearance in response to a change in a parameter associated with wound exudate,
- wherein the fibers comprise a plurality of sensor particles, the sensor particles comprising one or more indicator compounds including pH-sensitive dye, glucose-sensitive dye, lactate-sensitive dye, or any combination thereof, configured to undergo the change in appearance in response to the change in the parameter associated with the wound exudate, and
- wherein
- the sensor particles in the fibers of the first region comprise the pH-sensitive dye,
- the sensor particles in the fibers of the second region comprise the glucose-sensitive dye,
- the sensor particles in the fibers of the third region comprise the lactate-sensitive dye, and
- the sensor particles in the fibers of the fourth region are dye-free;
- and
- a supply of therapeutic agent configured to diffuse the therapeutic agent from the wound covering into a wound when the wound covering is placed on the wound.
7 more elements
Dependencies are inferred from the claim text.