Microfluidic chip and fabrication method
AssigneeShanghai Tianma Micro-Electronics Co., Ltd.
InventorsWei Li, Baiquan Lin, Kaidi Zhang, Yunfei Bai, Ping Su, Kerui Xi, Zhenyu Jia
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Abstract
A microfluidic chip and a fabrication method of the microfluidic chip are provided. The microfluidic chip includes an array substrate, and a hydrophobic layer disposed on a side of the array substrate. The hydrophobic layer includes at least one through-hole, and a through-hole of the at least one through-hole penetrates through the hydrophobic layer along a direction perpendicular to a plane of the array substrate. The microfluidic chip also includes at least one hydrophilic structure. A hydrophilic structure of the at least one hydrophilic structure is disposed in the through-hole.
Claims19
A microfluidic chip, comprising:
- an array substrate, including:
- a base substrate,
- a circuit layer, disposed on a side of the base substrate, and
- an electrode layer, disposed on a side of the circuit layer away from the base substrate, wherein the electrode layer includes a plurality of driving electrodes;
- a hydrophobic layer, disposed on a side of the array substrate including the plurality of driving electrodes, wherein the hydrophobic layer includes at least one through-hole, and a through-hole of the at least one through-hole penetrates through the hydrophobic layer along a direction perpendicular to a plane of the array substrate;
- and
- at least one hydrophilic structure, wherein a hydrophilic structure of the at least one hydrophilic structure is disposed in the through-hole,
- wherein in a plane parallel to the base substrate, the at least one hydrophilic structure is disposed between adjacent two driving electrodes of the plurality of driving electrodes.
A microfluidic chip, comprising:
- an array substrate;
- a hydrophobic layer, disposed on a side of the array substrate, wherein the hydrophobic layer includes at least one through-hole, and a through-hole of the at least one through-hole penetrates through the hydrophobic layer along a direction perpendicular to a plane of the array substrate;
- and
- at least one hydrophilic structure, wherein a hydrophilic structure of the at least one hydrophilic structure is disposed in the through-hole, wherein:
- the hydrophilic structure is made of a material including one or more of silicon oxide, silicon nitride, polyvinylpyrrolidone and sodium hydroxide.
A microfluidic chip, comprising:
- an array substrate;
- a hydrophobic layer, disposed on a side of the array substrate, wherein the hydrophobic layer includes at least one through-hole, and a through-hole of the at least one through-hole penetrates through the hydrophobic layer along a direction perpendicular to a plane of the array substrate;
- and
- at least one hydrophilic structure, wherein a hydrophilic structure of the at least one hydrophilic structure is disposed in the through-hole,
- wherein the array substrate includes:
- a base substrate,
- a circuit layer, disposed on a side of the base substrate, wherein the circuit layer includes a plurality of first transistors,
- an electrode layer, disposed on a side of the circuit layer away from the base substrate, wherein the electrode layer includes a plurality of driving electrodes, and a driving electrode of the plurality of driving electrodes is electrically connected to a first transistor of the plurality of first transistors, and
- an insulating layer, disposed on a side of the electrode layer away from the base substrate, wherein the hydrophobic layer is disposed on a side of the insulating layer away from the base substrate.
A fabrication method of a microfluidic chip, comprising:
- forming an array substrate by:
- providing a base substrate,
- forming a circuit layer on a side of the base substrate, and
- forming an electrode layer on a side of the circuit layer away from the base substrate, wherein the electrode layer includes a plurality of driving electrodes;
- forming a hydrophilic layer on a side of the array substrate including the plurality of driving electrodes;
- forming a first photoresist pattern on a side of the hydrophilic layer away from the array substrate, wherein the first photoresist pattern corresponds to a region of a to-be-formed hydrophilic structure in the hydrophilic layer;
- etching the hydrophilic layer using the first photoresist pattern as a mask to form at least one hydrophilic structure;
- forming a hydrophobic layer on the side of the array substrate where the at least one hydrophilic structure is formed, wherein the hydrophobic layer includes at least one through-hole, along a direction perpendicular to a plane of the array substrate, a through-hole of the at least one through-hole penetrates through the hydrophobic layer, and a hydrophilic structure of the at least one hydrophilic structure and the first photoresist pattern are located in the through-hole,
- wherein, in a plane parallel to the base substrate, the at least one hydrophilic structure is disposed between adjacent two driving electrodes of the plurality of driving electrodes;
- and
- removing the first photoresist pattern.
Dependencies are inferred from the claim text.