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AssigneeDionex Corporation
InventorsKannan Srinivasan, Mrinal Sengupta, Yan Liu, Christopher A. Pohl, Nebojsa Avdalovic
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Systems and methods for inhibiting translocation of ions across ion exchange barriers include an eluent generator having an ion source reservoir with a first electrode, an eluent generation chamber with a second electrode, an ion exchange barrier disposed therebetween, and means for reversing the polarity of a voltage or current applied across the first and second electrodes. A first polarity voltage or current applied across the electrodes generates an electric field that promotes translocation of eluent counter ions from the reservoir across the barrier, where the counter ions combine with eluent ions electrolytically generated in the chamber. By reversing the polarity of the voltage or current across the electrodes, the resulting electric field inhibits translocation of counter ions across the barrier from the reservoir into the chamber. Reverse voltage or current bias reduces counter ion concentration in the resting chamber to prevent exhaustion of ion suppressor capacity during start up.
A method of inhibiting translocation of an eluent in a liquid source through an ion exchange barrier of an ion exchange chromatography system, the method comprising:
Dependencies are inferred from the claim text.