Continuous synthesis method for 1, 1′-bicyclic [1.1.1]pentane-1,3-diethyl ketone compounds

A continuous synthesis method for compounds of formula (III):

• wherein the continuous synthesis method comprises:
• continuously conveying raw material A and raw material B to a continuous reaction device for a continuous photochemical reaction under irradiation of a light source to obtain the compounds, and controlling the reaction temperature in the continuous reaction device by a temperature control device during the continuous photochemical reaction, wherein the light source is an LED lamp with a wavelength of 300 to 350 nm, the raw material A has a structure represented by formula (I), and the raw material B has a structure represented by formula (II):
• in formula (I) and formula (III), R1, R2, and R3 are each independently selected from hydrogen, benzyl, alkyl, aryl, halogen, ester group, carboxyl or hydroxy, and at least one of R1, R2 and R3 is not hydrogen;
• in formula (II) and formula (III), R4 and R5 are each independently selected from hydrogen, alkyl or aryl;
• during the continuous photochemical reaction, the continuous synthesis method further comprises continuously conveying a cosolvent to the continuous reaction device, the cosolvent is one or more selected from a group consisting of methanol, ethanol, ethyl acetate, ethyl formate, acetone, butanone and acetonitrile.