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US 12,129,221 B2Granted
Difluoro phenyl amide RIP1 inhibitor
AssigneeSironax Ltd.
InventorsZhiyuan Zhang, Yaning Su, Yi Yang, Guozheng Wang, Wendong Liu, Yongfen Ma, Yan Ren
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Abstract
The disclosed compounds inhibit cellular necrosis, and include corresponding sulfonamides, prodrugs and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.
Claims4
An amide compound of structure:
- or a pharmaceutically acceptable salt, hydrate, or stereoisomer thereof.
Dependencies are inferred from the claim text.