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US 12,122,918 B2Granted
Drug that reacts with acrolein, use thereof and novel compound
AssigneeRiken
InventorsKatsunori Tanaka, Ambara Rachmat Pradipta
Life of this patent
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Abstract
Provided are, for example, (i) a drug that reacts with acrolein and (ii) a use thereof. A drug that reacts with acrolein in accordance with an embodiment of the present invention contains a compound having a chemical structure represented by Formula (1):
Claims10
A drug that reacts with acrolein,
- said drug comprising:
- a compound having a chemical structure represented by Formula (1):
- wherein
- R1 and R2 each independently represent a hydrogen atom, a halogen atom, or an alkyl group that has 1 to 5 carbon atoms and that may be substituted by at least one halogen atom, provided that at least one of R1 and R2 is the alkyl group having 1 to 5 carbon atoms;
- R3, R4, and R each independently represent a hydrogen atom, a halogen atom, a hydroxy group, a thiol group, an amino group that may have a substituent, an alkoxy group having 1 to 5 carbon atoms, an alkylthio group having 1 to 5 carbon atoms, or an alkyl group having 1 to 5 carbon atoms provided that a hydrogen atom constituting the alkyl group may be substituted by a substituent selected from a halogen atom, a hydroxy group, and an amino group that may have a substituent;
- n is an integer of not less than 1 and not more than 5;
- and
- is a binding site to another chemical structure.
5 more elements
A compound represented by Formula (10):
- wherein
- R1 and R2 each independently represent a hydrogen atom, a halogen atom, or an alkyl group that has 1 to 5 carbon atoms and that may be substituted by at least one halogen atom, provided that at least one of R1 and R2 is the alkyl group having 1 to 5 carbon atoms;
- R3, R4, and R each independently represent a hydrogen atom, a halogen atom, a hydroxy group, a thiol group, an amino group that may have a substituent, an alkoxy group having 1 to 5 carbon atoms, an alkylthio group having 1 to 5 carbon atoms, or an alkyl group having 1 to 5 carbon atoms provided that a hydrogen atom constituting the alkyl group may be substituted by a substituent selected from a halogen atom, a hydroxy group, and an amino group that may have a substituent;
- n is an integer of not less than 1 and not more than 5;
- and
- a rhodamine-based coloring reagent is bound at .
3 more elements
Dependencies are inferred from the claim text.