Methods of carbon-carbon bond fragmentation

A method of making a compound, comprising:

• providing a starting material comprising an sp3-hybridized carbon and an sp2-hybridized carbon, wherein the sp3-hybridized carbon and the sp2-hybridized carbon are connected by a single bond;
• placing the starting material in a reaction vessel, thereby forming a reaction mixture;
• and
• cleaving the single bond, wherein cleaving the single bond comprises:
• contacting the reaction mixture with an oxidant;
• and
• contacting the reaction mixture with a transition metal salt;
• wherein the method further comprises quenching the reaction mixture with a radical quencher.