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US 12,116,553 B2Granted
Polypeptide variants
AssigneeThe Procter & Gamble Company
InventorsLars Beier, Lars Henrik Oestergaard, Annette Helle Johansen, Klaus Gori, Thomas Holberg Blicher, Gernot J. Abel, Steen Krogsgaard, Jens E Nielsen, Lars Giger, Neil Joseph Lant
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Abstract
Detergent compositions including polypeptide variants and methods of cleaning and/or treatment of surfaces using such compositions, and fabric treatment compositions including polypeptide variants. The compositions may include surfactants: anionic, nonionic and/or cationic.
Claims20
A detergent composition comprising
- a) a variant of a DNase parent, wherein the parent is SEQ ID NO:
- 1, and wherein the variant comprises a substitution Q12S, Q12V, or Q12E, wherein the variant has a sequence identity to SEQ ID NO:
- 1 of about 85% or more, but less than 100% and the variant has DNase activity;
- and
- b) from about 0.01 to about 99.9 wt % of an adjunct.
2 more elements
A method for making a detergent composition comprising obtaining a DNase variant, comprising;
- a) introducing into a parent DNase of SEQ ID NO:1 an alteration at position 12, comprising Q12S, Q12V, or Q12E to form the DNase variant, wherein the DNase variant has DNase activity and about 85% or more, but less than 100% sequence identity to SEQ ID NO:1,
- b) recovering the DNase variant;
- and
- c) mixing the DNase variant with a detergent composition adjunct.
1 more element
Dependencies are inferred from the claim text.