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US 12,116,355 B2Granted
Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia
AssigneeH. Lundbeck A/S
InventorsMorten Jorgensen, Peter Hongaard Andersen, Klaus Gjervig Jensen
Life of this patent
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Abstract
The present invention relates to deuterated 1-piperazino-3-phenyl-indanes and salts thereof with activity at dopamine receptors D1 and D2 as well as the 5HT2 receptors in the central nervous system, to medicaments comprising such compounds as active ingredients, to the use of such compounds in the treatment of diseases in the central nervous system, and to methods of treatment comprising administration of such compounds.
Claims7
A hydrogen maleate salt of a deuterium enriched compound of formula Y:
- wherein,
- R1-R10 are independently hydrogen or deuterium, wherein at least two of R1-R10 are deuterium.
Dependencies are inferred from the claim text.