Hydrocortisone acetate suppository formulation for treatment of disease
AssigneeCristcot LLC
InventorsJennifer J. Davagian, Raj Devarajan
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Abstract
The present invention relates, in various embodiments, to formulations comprising hydrocortisone and silicon dioxide. In additional embodiments, the invention relates to suppositories comprising hydrocortisone and silicon dioxide. The formulations of the present invention are useful for administration to patients who have gastrointestinal diseases and disorders such as, for example, inflammatory bowel disease.
Claims17
A formulation comprising about 0.5% to about 5% by weight hydrocortisone acetate, about 0.1% to about 5% by weight colloidal silicon dioxide, and a glyceride base comprising lecithin, wherein the formulation has a melting temperature in the range of about 35° C. to about 39° C.
Dependencies are inferred from the claim text.