Immunological adjuvant composition, preparation method and application thereof
AssigneeLuoyang Seiwei Biotechnologies Co., Ltd.
InventorsKegong Tian, Yongmei Liu, Xuke Zhang
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Abstract
The present disclosure provides an adjuvant composition containing 0.2%-15% w/v carbomer, 0.1%-0.5% w/v lecithin, and 0.03%-0.2% w/v ginsenoside. The adjuvant composition of the present disclosure cannot only ensure the long-term clarification and/or stability of the vaccine, but also can effectively stimulate the inactivated antigens and subunit antigens therein to produce high-titer antibodies for immune protection. The inactivated vaccines or subunit vaccines prepared by the adjuvant composition of the present disclosure can be used as a diluent for freeze-dried live virus antigens and has no toxic effect on the live virus antigens.
Claims11
A composition comprising 0.2%-0.5% w/v carbomer, 0.1%-0.5% w/v Lecithin, and 0.03%-0.2% w/v ginseng stem-leaf saponins.
A vaccine composition comprising 30-70% w/w of a composition including 0.2%-0.5% w/v carbomer, 0.1%-0.5% w/v Lecithin and 0.03%-0.2% w/v ginseng stem-leaf saponins and an immune amount of inactivated antigen or subunit antigen.
A vaccine composition comprising 30-70% w/w of a composition including 0.2%-0.5% w/v carbomer, 0.1%-0.5% w/v Lecithin and 0.03%-0.2% w/v ginseng stem-leaf saponins, an immune amount of inactivated antigen or subunit antigen and an immune amount of live virus vaccine.
Dependencies are inferred from the claim text.