Long acting amylin receptor agonists and uses thereof
AssigneeEli Lilly and Company
InventorsMilata Mary Abraham, Daniel Anthony Briere, Lili Guo, Samantha Grace Lyons Keyser, John Lee, Hongchang Qu
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Abstract
The present disclosure relates to the field of medicine. More particularly, the disclosure is in the field of treatment of diabetes, obesity and/or chronic weight management, dyslipidemia and/or NASH. The disclosure relates to compounds that agonize the amylin receptor and can lower food intake, body weight, glucose and/or triglycerides, so can be used to treat diabetes, obesity, and/or dyslipidemia. The present disclosure also includes pharmaceutical compositions containing such compounds and therapeutic uses of such compounds and compositions.
Claims20
A compound comprising SEQ ID NO:2 or a pharmaceutically acceptable salt thereof.
A compound comprising SEQ ID NO:4 or a pharmaceutically acceptable salt thereof.
A compound comprising SEQ ID NO:6 or a pharmaceutically acceptable salt thereof.
A compound comprising SEQ ID NO:8 or a pharmaceutically acceptable salt thereof.
A compound consisting of SEQ ID NO:2 or a pharmaceutically acceptable salt thereof.
A compound consisting of SEQ ID NO:4 or a pharmaceutically acceptable salt thereof.
A compound consisting of SEQ ID NO:6 or a pharmaceutically acceptable salt thereof.
A compound consisting of SEQ ID NO:8 or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.