# US 12,112,477 B2 · Semi-automated system for real-time wound image segmentation and photogrammetry on a mobile platform

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- Number: US 12,112,477 B2
- Document ID: US12112477B2
- Status: Granted
- Kind: B2
- Application number: 18/241,538
- Filed: 2023-09-01
- Published: 2023-12-21
- Granted: 2024-10-08
- Earliest claimed: 2016-06-28
- Assignees: Solventum Intellectual Properties Company
- Applicants: Solventum Intellectual Properties Company
- Inventors: Brett L. Moore
- Web page: https://patentgrep.com/patent/US12112477B2

## CPC

- G06T 7/0012: {Biomedical image inspection}
- A61B 5/0013: {Medical image data (A61B1/00011, A61B6/56, A61B8/56 take precedence)}
- A61B 5/0077: {Devices for viewing the surface of the body, e.g. camera, magnifying lens}
- A61B 5/445: {Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore}
- A61B 5/7475: {User input or interface means, e.g. keyboard, pointing device, joystick}
- G06T 7/11: Region-based segmentation
- G06T 7/12: Edge-based segmentation
- G06T 7/149: involving deformable models, e.g. active contour models
- G16H 30/20: for handling medical images, e.g. DICOM, HL7 or PACS
- G16H 30/40: for processing medical images, e.g. editing
- G06T 2207/20104: Interactive definition of region of interest [ROI]
- G06T 2207/20116: Active contour; Active surface; Snakes
- G06T 2207/30088: Skin; Dermal
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA

## Abstract

In one example embodiment, a wound imaging system includes a user interface, a computer processor, and an active contouring module. The user interface is configured to display an image of a wound acquired by the wound imaging system and selectively receive inputs from a user defining an initial perimeter of the wound. An active contouring module is configured to operate on the computer processor to receive the inputs defining the initial perimeter of the wound, identify features of the image on opposing sides of the initial perimeter of the wound, and identify an actual perimeter of the wound based on the initial perimeter of the wound and the identified features. The user interface is further configured to display, on the image of the wound, the actual perimeter of the wound as identified by the active contouring module and selectively receive inputs from the user to modify the actual perimeter of the wound.

## Claims

### Claim 1

A wound imaging system, comprising:
a non-transitory computer readable medium for storing a wound image; and
a computer processor configured to
output for display the wound image,
selectively receive via a user interface a first input from a user defining an initial perimeter of a wound displayed in the wound image;
identify features of the wound image on opposing sides of the initial perimeter of the wound,
identify an actual perimeter of the wound based on the first input and the identified features,
output for display a graphical representation of the identified actual perimeter of the wound,
identify a number of pixels enclosed by the actual perimeter of the wound,
detect an image scale-identification marker present in the wound image,
identify a size of each pixel based on the image scale-identification marker,
calculate a wound area based on the number of pixels enclosed by the actual perimeter of the wound,
receive a depth of the wound, and
calculate a volume of the wound based on the wound area and the depth.

### Claim 2 (depends on 1)

The system of claim 1, wherein the depth comprises a second input from the user.

### Claim 3 (depends on 1)

The system of claim 1, wherein the computer processor determines the depth of the wound from a three-dimensional image of the wound.

### Claim 4 (depends on 1)

The system of claim 1, wherein the computer processor is further configured to selectively receive via the user interface a second input from the user to modify the actual perimeter of the wound.

### Claim 5 (depends on 1)

The system of claim 1, wherein the computer processor is further configured to selectively receive via the user interface a second input from the user to confirm the actual perimeter of the wound.

### Claim 6 (depends on 1)

The system of claim 1, further comprising a touchscreen display, and wherein the user interface includes a graphical user interface for selectively receiving the first input and a second input from the user via the touchscreen display.

### Claim 7 (depends on 1)

The system of claim 1, wherein the first input includes at least one of a plurality of points selected around the wound and an outline traced around the wound.

### Claim 8 (depends on 7)

The system of claim 7, wherein the plurality of points define a polygon around the wound.

### Claim 9 (depends on 1)

The system of claim 1, wherein the first input includes at least one tap to indicate that the initial perimeter of the wound is complete.

### Claim 10 (depends on 1)

The system of claim 1, wherein the initial perimeter corresponds to an initial active contour.

### Claim 11 (depends on 10)

The system of claim 10, wherein the computer processor is further configured to determine a final active contour using the initial active contour, wherein the final active contour corresponds to the actual perimeter of the wound.

### Claim 12 (depends on 11)

The system of claim 11, wherein the computer processor is configured to determine the final active contour by comparing regions outside of the initial active contour with regions inside the initial active contour.

### Claim 13 (depends on 12)

The system of claim 12, wherein comparing the regions outside of the initial active contour with the regions inside the initial active contour includes performing an iterative energy minimization process on the initial active contour.

### Claim 14 (depends on 13)

The system of claim 13, wherein the iterative energy minimization process includes (i) calculating an energy value associated with the initial active contour and (ii) determining whether modifying the initial active contour decreases the energy value.