# US 12,109,536 B2 · Particle capturing device and particle capturing method > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,109,536 B2 - Document ID: US12109536B2 - Status: Granted - Kind: B2 - Application number: 17/287,705 - Filed: 2019-10-30 - Published: 2021-11-18 - Granted: 2024-10-08 - Earliest claimed: 2018-11-02 - Assignees: Tokyo Ohka Kogyo Co., Ltd. - Applicants: Tokyo Ohka Kogyo Co., Ltd. - Inventors: Takashi Ohsaka - Web page: https://patentgrep.com/patent/US12109536B2 ## CPC - B01D 61/20: Accessories; Auxiliary operations - C12M 47/04: {Cell isolation or sorting (purging biological preparations of unwanted cells C12N5/0081, determining the presence or kind of microorganism C12Q1/04)} - B01D 61/147: {Microfiltration} - B01D 61/18: Apparatus therefor - B01D 63/088: {Microfluidic devices comprising semi-permeable flat membranes} - B01D 67/0034: {by micromachining techniques, e.g. using masking and etching steps, photolithography} - B01L 3/50255: {Multi-well filtration} - B01L 3/505: {Flexible containers without fluid transport within} - G01N 1/2813: {Producing thin layers of samples on a substrate, e.g. smearing, spinning-on (G01N1/30 takes precedence)} - B01D 2221/10: Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues - B01D 2325/08: Patterned membranes - B01L 2200/0647: Handling flowable solids, e.g. microscopic beads, cells, particles - B01L 2200/0668: Trapping microscopic beads - B01L 2200/12: Specific details about manufacturing devices - B01L 2300/0609: Holders integrated in container to position an object - B01L 2300/0681: Filter - B01L 2300/123: Flexible; Elastomeric - B01L 2400/049: vacuum - G01N 2001/2833: {Collecting samples on a sticky, tacky, adhesive surface} - B01D: SEPARATION (separating solids from solids by wet methods B03B, B03D; by pneumatic jigs or tables B03B; by other dry methods B07; magnetic or electrostatic separation of solid materials from solid materials or fluids, separation by high-voltage electric fields B03C; centrifuges, vortex apparatus B04; presses per se for squeezing-out liquid from liquid-containing material B30B9/02; treatment of water C02F, e.g. softening by ion-exchange C02F1/42; {arrangements of air intake cleaners in gas turbine plants F02C7/05} ; arrangements or mounting of filters in air-conditioning, air-humidification or ventilation F24F13/28) - C12M: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; {APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS} - B01L: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) ## Abstract A particle capturing device including a substrate, a particle capturing film configured to capture particles, and a support configured to support the particle capturing film when tension is applied to the particle capturing film such that the particle capturing film is in parallel with the substrate and a space is formed between the particle capturing film and the substrate. ## Claims ### Claim 1 A particle capturing device comprising: a substrate; a particle capturing film configured to capture particles; and a support configured to support the particle capturing film when tension is applied to the particle capturing film such that the particle capturing film is in parallel with the substrate and a space is formed between the particle capturing film and the substrate; and an expansion member configured to expand the support such that the tension is applied to the particle capturing film. ### Claim 2 (depends on 1) A particle capturing device according to claim 1, wherein the expansion member is a film expansion member configured to expand the particle capturing film such that the tension is applied to the particle capturing film. ### Claim 3 (depends on 1) The particle capturing device according to claim 1, wherein the space is filled with a liquid. ### Claim 4 (depends on 1) The particle capturing device according to claim 1, wherein the particle capturing film includes a capturing portion having a size which enables capturing of one particle, and a communication hole having a size which does not allow passage of one particle and allowing the capturing portion and the space to communicate with each other. ### Claim 5 (depends on 4) The particle capturing device according to claim 4, wherein the particle capturing film includes a first layer having the communication hole, and a second layer which is connected to the communication hole and has a through hole having the same size as that of an outer shape of the capturing portion. ### Claim 6 A particle capturing device, comprising: a substrate; a particle capturing film configured to capture particles; a support configured to support the particle capturing film in a state of applying tension to the particle capturing film such that the particle capturing film is in parallel with the substrate and a space is formed between the particle capturing film and the substrate; and an inclination support member configured to support the support in a state where the support is inclined with respect to the substrate such that the tension is applied to the particle capturing film. ### Claim 7 (depends on 6) The particle capturing device according to claim 6, wherein the space is filled with a liquid. ### Claim 8 (depends on 6) The particle capturing device according to claim 6, wherein the particle capturing film includes a capturing portion having a size which enables capturing of one particle, and a communication hole having a size which does not allow passage of one particle and allowing the capturing portion and the space to communicate with each other. ### Claim 9 (depends on 8) The particle capturing device according to claim 8, wherein the particle capturing film includes a first layer having the communication hole, and a second layer which is connected to the communication hole and has a through hole having the same size as that of an outer shape of the capturing portion. ### Claim 10 A particle capturing device, comprising: a substrate; a particle capturing film configured to capture particles; a support configured to support the particle capturing film in a state of applying tension to the particle capturing film such that the particle capturing film is in parallel with the substrate and a space is formed between the particle capturing film and the substrate; and a liquid-absorbing swelling member configured to be bonded to the support and increase in volume by absorbing a liquid such that the tension is applied to the particle capturing film. ### Claim 11 (depends on 10) The particle capturing device according to claim 10, wherein the space is filled with a liquid. ### Claim 12 (depends on 10) The particle capturing device according to claim 10, wherein the particle capturing film includes a capturing portion having a size which enables capturing of one particle, and a communication hole having a size which does not allow passage of one particle and allowing the capturing portion and the space to communicate with each other. ### Claim 13 (depends on 12) The particle capturing device according to claim 12, wherein the particle capturing film includes a first layer having the communication hole, and a second layer which is connected to the communication hole and has a through hole having the same size as that of an outer shape of the capturing portion.