# US 12,109,437 B2 · Medical device for radiotherapy and method of manufacturing the same

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- Number: US 12,109,437 B2
- Document ID: US12109437B2
- Status: Granted
- Kind: B2
- Application number: 17/292,850
- Filed: 2019-11-13
- Published: 2021-12-23
- Granted: 2024-10-08
- Earliest claimed: 2018-11-14
- Assignees: Hopitaux Universitaires De Geneve
- Applicants: HôPitaux Universitaires De GenèVe
- Inventors: Giovanna Dipasquale
- Web page: https://patentgrep.com/patent/US12109437B2

## CPC

- A61N 5/1049: {for verifying the position of the patient with respect to the radiation beam}
- A61N 5/107: {in real time, i.e. during treatment}
- A61B 90/17: for soft tissue, e.g. breast-holding devices
- B29C 64/386: Data acquisition or data processing for additive manufacturing
- B33Y 50/00: Data acquisition or data processing for additive manufacturing
- B33Y 80/00: Products made by additive manufacturing
- A61B 2090/101: {for stereotaxic radiosurgery}
- A61N 2005/1094: {Shielding, protecting against radiation}
- A61N 2005/1096: {Elements inserted into the radiation path placed on the patient, e.g. bags, bolus, compensators}
- A61N 2005/1097: {Means for immobilizing the patient}
- B29K 2083/00: Use of polymers having silicon, with or without sulfur, nitrogen, oxygen, or carbon only, in the main chain, as moulding material
- B29L 2031/753: {Medical equipment; Accessories therefor (bloodbags, medical bags B29L2031/7148; artificial eyes B29L2011/0008)}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- B29C: SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING (making preforms B29B11/00; making laminated products by combining previously unconnected layers which become one product whose layers will remain together B32B37/00 - B32B41/00)
- B33Y: ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B29K: INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR {MOULDS, } REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29L: INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES

## Abstract

The present relates to a positioning and shaping shell manufacturing method for manufacturing a positioning and shaping shell comprising a positioning step consisting in positioning and supporting a target body portion with a transparent body shaper in a predetermined position on a positioning board presenting at least one transparent portion permitting scanning through it, an image acquisition step consisting in a target body portion surface scan imaging also via the transparent portion of the board and said transparent body support, a software computing step where the acquired image data are sent and processed in a processing unit, and a producing step consisting in producing a 3D positioning and shaping shell model via additive or subtractive manufacturing method based in the processed image data.

## Claims

### Claim 1

Positioning and shaping shell manufacturing method for manufacturing a positioning and shaping shell comprising:
a positioning step including positioning and supporting a target body portion with a transparent body shaper in a predetermined position on a positioning board, the positioning board presenting at least one transparent portion permitting scanning through it,
an image acquisition step including partially imaging the target body portion surface via the transparent portion of the positioning board and said transparent body shaper to acquire image data,
a software computing step where the acquired image data are sent and processed in a processing unit to generate processed image data, and
a producing step including producing a 3D positioning and shaping shell model via additive or subtractive manufacturing method based in the processed image data.

### Claim 2 (depends on 1)

Positioning and shaping shell manufacturing method according to claim 1, characterized in that the additive manufacturing method is chosen from the group of 3D printing, thermoforming, pin-matrix system shaping and the subtractive manufacturing method is chosen from the group of drilling, milling, turning and laser shaping.

### Claim 3 (depends on 1)

Positioning and shaping shell manufacturing method according to claim 1, characterized in that the target body portion is a breast.

### Claim 4 (depends on 1)

Positioning and shaping shell manufacturing method according to claim 1, characterized in that the image acquisition is performed using a surface scan imaging system selected from the group composed of a surface scanner, Magnetic Resonance Imaging System or Computer Tomography system.

### Claim 5 (depends on 1)

Transparent body shaper to be used in the positioning shell manufacturing method of claim 1 adapted to support and position a predetermined target body portion in a specific position adapted for an optimal medical treatment.

### Claim 6

Patient positioning device for use in a radiotherapy treatment process comprising:
a positioning board, and
a positioning and shaping shell manufactured by i) positioning and supporting a target body portion with a transparent body shaper in a predetermined position on a positioning board, the positioning board presenting at least one transparent portion permitting scanning through it, ii) at least partially imaging a target body portion surface via the transparent portion of the positioning board and said transparent body shaper, iii) processing acquired image data in a processing unit to generate processed image data, and iv) producing a 3D positioning and shaping shell model via additive or subtractive manufacturing method based in the processed image data and reproducing a patient's target body portion shape and adapted to be installed on the positioning board so as to receive and immobilize said target body portion.

### Claim 7 (depends on 6)

Patient positioning device according to claim 6, characterized in that the positioning and shaping shell comprises a hollow portion adapted to receive and house a specific bolus.

### Claim 8 (depends on 6)

Patient positioning device to claim 6, characterized in that the positioning and shaping shell is made of silicone.

### Claim 9 (depends on 6)

Patient positioning device according to claim 6, characterized in that the transparent portion of the positioning board is made of a transparent acrylic material.

### Claim 10 (depends on 6)

Patient positioning device according to claim 6, characterized in that it is adapted to position the patient in a prone position.

### Claim 11 (depends on 6)

Patient positioning device according to claim 6, characterized in that the positioning board comprises a tilting means adapted to tilt and/or move said target body portion.

### Claim 12 (depends on 6)

Patient positioning device according to claim 6, characterized in that it further comprises attaching means for attaching the positioning and shaping shell to the positioning board.

### Claim 13 (depends on 6)

Patient positioning device according to claim 6, characterized in that the positioning and shaping shell is adapted to shape the patient's target body portion.

### Claim 14 (depends on 6)

Patient positioning device according to claim 6, characterized in that the positioning and shaping shell is made of two complementary detachable elements.

### Claim 15 (depends on 6)

Patient positioning device according to claim 6, characterized in that it comprise other devices next to or in contact with the patient and with the transparent body shapers to position the patient as necessary, the devices chosen from the group of sensors, monitoring systems, detectors, feeding systems, anesthesia systems, treatment or imaging systems, cooling or heating systems, tracking systems, metamaterials and the same.

### Claim 16 (depends on 6)

Patient positioning device according to claim 6, characterized in that it is adapted to at least partially stop a radiotherapy beam and modulate radiation.

### Claim 17 (depends on 6)

Patient positioning device according to claim 6, characterized in that its capacity to immobilize said target body portion of a patient's body includes that it prevents patient body movements during treatments so that the patient's body can be translated/rotated during irradiation while avoiding collisions between the patient's body and a treatment machine.