# US 12,109,418 B2 · Segmented lead independent electrode control for sensing or adaptive stimulation > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,109,418 B2 - Document ID: US12109418B2 - Status: Granted - Kind: B2 - Application number: 17/522,612 - Filed: 2021-11-09 - Published: 2022-05-26 - Granted: 2024-10-08 - Earliest claimed: 2020-11-25 - Assignees: Medtronic, Inc. - Applicants: Medtronic, Inc. - Inventors: Brendan J. Young-Dixon; Thomas L Chouinard; Lance Beall - Web page: https://patentgrep.com/patent/US12109418B2 ## CPC - A61N 1/3605: {Implantable neurostimulators for stimulating central or peripheral nerve system} - A61N 1/36185: {Selection of the electrode configuration} - A61N 1/0529: {Electrodes for brain stimulation} - A61N 1/0534: {Electrodes for deep brain stimulation} - A61N 1/3606: {adapted for a particular treatment} - A61N 1/36139: {with automatic adjustment} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) ## Abstract An example system includes a lead including a first electrode disposed at a first level, a second electrode disposed at a second level, a first group of segmented electrodes disposed at a third level, and a second group of segmented electrodes disposed at a fourth level. The example system also includes a medical device configured to deliver symmetrical electrical stimulation to a patient via the first group of segmented electrodes and the second group of segmented electrodes and sense a response to the stimulation via the first electrode and the second electrode. ## Claims ### Claim 1 A neuromodulation system comprising: a stimulation generator configured to deliver symmetrical electrical stimulation through a plurality of stimulation electrodes, the plurality of stimulation electrodes comprising at least two of a first electrode, a second electrode, at least one segment electrode of a first group of segmented electrodes, or at least one segment electrode of a second group of segmented electrodes, wherein the symmetrical electrical stimulation comprises electrical stimulation of a same amplitude from each stimulation electrode of a respective pair of stimulation electrodes; a sensing channel configured to sense a response to the symmetrical electrical stimulation through a plurality of sense electrodes, the plurality of sense electrodes comprising at least two of the first electrode, the second electrode, at least one other segment electrode of the first group of segmented electrodes, or at least one other segment electrode of the second group of segmented electrodes, each of the plurality of sense electrodes being different than each of the plurality of stimulation electrodes; and processing circuitry configured to: control the stimulation generator to deliver the symmetrical electrical stimulation; determine a response to the symmetrical electrical stimulation via the sensing channel; and adjust at least one stimulation parameter of the symmetrical electrical stimulation based on the sensed response. ### Claim 2 (depends on 1) The neuromodulation system of claim 1, wherein the stimulation generator is configured to deliver the symmetrical electrical stimulation via at least one segment electrode of the second group of segmented electrodes and sense the response to the symmetrical electrical stimulation via the first electrode and the first group of segmented electrodes. ### Claim 3 (depends on 1) The neuromodulation system of claim 1, wherein the stimulation generator is configured to deliver the symmetrical electrical stimulation via at least one segment electrode of the first group of segmented electrodes and at least one segment electrode of the second group of segmented electrodes and sense the response to the symmetrical electrical stimulation via at least one other segment electrode of the first group of segmented electrodes and at least one other segment electrode of the second group of segmented electrodes. ### Claim 4 (depends on 1) The neuromodulation system of claim 1, wherein the stimulation generator is configured to deliver the symmetrical electrical stimulation via at least two of a first segment electrode of the first group of segmented electrodes, a first segment electrode of the second group of segment electrodes, the first electrode or the second electrode and sense the response to the symmetrical electrical stimulation via a second segment electrode of the first group of segmented electrodes and a second segment electrode of the second group of segmented electrodes. ### Claim 5 (depends on 1) The neuromodulation system of claim 1, wherein symmetrical electrical stimulation comprises electrical stimulation of a first amplitude through a first segment electrode of the first group of segmented electrodes and a corresponding first segment electrode of the second group of segmented electrodes, electrical stimulation of a second amplitude through a second segment electrode of the first group of segmented electrodes and a corresponding second segment electrode of the second group of segmented electrodes, and electrical stimulation of a third amplitude through a third segment electrode of the first group of segmented electrodes and a corresponding third segment electrode of the second group of segmented electrodes. ### Claim 6 (depends on 1) The neuromodulation system of claim 1, wherein symmetrical electrical stimulation comprises for each electrical stimulation amplitude of each segment electrode of the first group of segmented electrodes, a matching electrical stimulation amplitude for one segment electrode of the second group of segmented electrodes. ### Claim 7 (depends on 1) The neuromodulation system of claim 1, wherein symmetrical electrical stimulation comprises a total amplitude of electrical stimulation for each segment electrode of the first group segmented electrodes equaling a total amplitude of electrical stimulation for each segment electrode of the second group of segmented electrodes. ### Claim 8 (depends on 1) The neuromodulation system of claims 1, wherein the first group of segmented electrodes and the second group of segmented electrodes are configured to deliver the symmetrical stimulation via different segment electrodes over time to move the symmetrical stimulation around a longitudinal axis of a lead comprising the first group of segmented electrodes and the second group of segmented electrodes. ### Claim 9 (depends on 1) The neuromodulation system of claim 1, wherein the neuromodulation system comprises an adaptive deep brain stimulation system. ### Claim 10 (depends on 1) The neuromodulation system of claim 1, further comprising: a lead, wherein the lead comprises the first group of segmented electrodes, the second group of segmented electrodes, the first sensing electrode, and the second sensing electrode. ### Claim 11 A method of providing neuromodulation comprising: generating a symmetrical electrical stimulation signal, the symmetrical electrical stimulation comprising electrical stimulation of a same amplitude from each stimulation electrode of a respective pair of stimulation electrodes; delivering the symmetrical electrical stimulation signal through a plurality of stimulation electrodes, the plurality of stimulation electrodes comprising at least two of a first electrode, a second electrode, at least one segment electrode of a first group of segmented electrodes or at least one segment electrode of a second group of segmented electrodes to a patient; sensing a response to the symmetrical electrical stimulation signal through a plurality of sense electrodes, the plurality of sense electrodes comprising at least two of the first electrode, the second sensing electrode, at least one other segment electrode of a first group of segmented electrodes or at least one other segment electrode of a second group of segmented electrodes, each of the plurality of sense electrodes being different than each of the plurality of stimulation electrodes; and adjusting at least one stimulation parameter of the symmetrical electrical stimulation signal based on the sensed response. ### Claim 12 (depends on 11) The method of claim 11, wherein the delivering the symmetrical electrical stimulation is via at least one segment electrode of the second group of segmented electrodes and the sensing the response to the symmetrical electrical stimulation is via the first electrode and the first group of segmented electrodes. ### Claim 13 (depends on 11) The method of claim 11, wherein the delivering the symmetrical electrical stimulation is via at least one segment electrode of the first group of segmented electrodes and at least one segment electrode of the second group of segmented electrodes and the sensing the response to the symmetrical electrical stimulation is via at least one other segment electrode of the first group of segmented electrodes and at least one other segment electrode of the second group of segmented electrodes. ### Claim 14 (depends on 11) The method of claim 11, wherein the delivering the symmetrical electrical stimulation is via at least two of a first segment electrode of the first group of segmented electrodes, a first segment electrode of the second group of segment electrodes, the first electrode or the second electrode and the sensing the response to the symmetrical electrical stimulation via a second segment electrode of the first group of segmented electrodes and a second segment electrode of the second group of segmented electrodes. ### Claim 15 (depends on 11) The method of claim 11, wherein symmetrical electrical stimulation signal comprises electrical stimulation of a first amplitude through a first segment electrode of the first group of segmented electrodes and a corresponding first segment electrode of the second group of segmented electrodes, electrical stimulation of a second amplitude through a second segment electrode of the first group of segmented electrodes and a corresponding second segment electrode of the second group of segmented electrodes, and electrical stimulation of a third amplitude through a third segment electrode of the first group of segmented electrodes and a corresponding third segment electrode of the second group of segmented electrodes. ### Claim 16 (depends on 11) The method of claim 11, wherein symmetrical electrical stimulation comprises for each electrical stimulation amplitude of each segment electrode of the first group of segmented electrodes, a matching electrical stimulation amplitude for one segment electrode of the second group of segmented electrodes. ### Claim 17 (depends on 11) The method of claim 11, wherein symmetrical electrical stimulation comprises a total amplitude of electrical stimulation for each segment electrode of the first group of segmented electrodes equaling a total amplitude of electrical stimulation for each segment electrode of the second group of segmented electrodes. ### Claim 18 (depends on 11) The method of claim 11, wherein the first group of segmented electrodes and the second group of segmented electrodes are configured to deliver the symmetrical stimulation over different segment electrodes over time to move the symmetrical stimulation around a longitudinal axis of a lead comprising the first group of segmented electrodes and the second group of segmented electrodes. ### Claim 19 A non-transitory storage medium storing instructions, which, when executed, cause processing circuitry to: control a stimulation generator to generate a symmetrical electrical stimulation signal, the symmetrical electrical stimulation comprising electrical stimulation of a same amplitude from each stimulation electrode of a respective pair of stimulation electrodes; control the stimulation generator to deliver the symmetrical electrical stimulation signal through a plurality of stimulation electrodes, the plurality of stimulation electrodes comprising at least two of a first electrode, a second electrode, at least one segment electrode of a first group of segmented electrodes, or at least one segment electrode of a second group of segmented electrodes to a patient; sense a response to the symmetrical electrical stimulation signal through a plurality of sense electrodes, the plurality of sense electrodes comprising at least two of the first electrode, the second electrode, at least one other segment electrode of the first group of segmented electrodes, or at least one other segment electrode of the second group of segmented electrodes, each of the plurality of sense electrodes being different than each of the plurality of stimulation electrodes; and control the stimulation generator to adjust at least one stimulation parameter of the symmetrical electrical stimulation signal based on the sensed response. ### Claim 20 (depends on 1) The neuromodulation system of claim 1, wherein for each respective pair of stimulation electrodes, a first stimulation electrode is a same distance from a first sense electrode of a sense electrode pair as a second stimulation electrode is from a second sense electrode of the sense electrode pair.