# US 12,109,398 B2 · Torsion spring driven injection device

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- Number: US 12,109,398 B2
- Document ID: US12109398B2
- Status: Granted
- Kind: B2
- Application number: 17/286,845
- Filed: 2019-10-28
- Published: 2021-12-16
- Granted: 2024-10-08
- Earliest claimed: 2018-10-30
- Assignees: Novo Nordisk A/S
- Applicants: Novo Nordisk A/S
- Inventors: Claus Urup Gjoedesen; Niels Christian Egholm Soerensen; Kim Roennow Sejtzer
- Web page: https://patentgrep.com/patent/US12109398B2

## CPC

- A61M 5/2033: {Spring-loaded one-shot injectors with or without automatic needle insertion (multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287)}
- A61M 5/31526: {by means of stepwise axial movements, e.g. ratchet mechanisms or detents}
- A61M 5/31543: {piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change}
- A61M 5/3157: {Means providing feedback signals when administration is completed (A61M5/20 takes precedence)}
- A61M 5/31585: {the component being manually operated or triggered by an axially moving actuator operated by user, e.g. an axially movable injection button}
- A61M 5/31591: {Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means}
- A61M 5/31595: {Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking}
- A61M 2005/2073: {preventing premature release, e.g. by making use of a safety lock}
- A61M 2005/2407: {from the rear}
- A61M 2005/3126: {related to dosing}
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

The invention relates to a torsion spring driven injection device for ejecting set doses of a liquid drug. In a first aspect the torsion spring driven injection device is provided with a blocking structure which is operated by the rotatable display element such that the set dose can only be expelled when a certain minimum dose size has been set. In a second aspect the torsion spring driven injection device is provided with a release mechanism which secures that the set dose can only be expelled as one single full dose in one stroke. The two aspects can easily be combined such that the predetermined minimum dose size most be expelled as one single dose.

## Claims

### Claim 1

A torsion spring driven injection device for ejecting at least one dose of a liquid drug comprising:
a housing structure securing a container containing the liquid drug to be ejected,
a rotational dose setting element operable by a user for setting the size of a set dose to be ejected,
a rotatable dose setting structure transferring rotation from the dose setting element to a straining of a torsion spring such that a torque is stored in the torsion spring upon rotation of the dose setting element,
a rotatable display element arranged to follow rotation of the dose setting structure and helically movable relatively to the housing structure from an initial position to a dosing position, wherein the set dose is indicated by indicia carried by the rotatable display element,
a piston rod arranged in a longitudinal direction (X) and movable in a distal direction to expel the set dose from the container,
a rotatable drive element engaging the piston rod and adapted to move the piston rod in the distal direction upon rotation of the rotatable drive element,
an axially movable release element for releasing the torque stored in the torsion spring to rotate the rotatable drive element,
wherein,
the injection device further comprises a blocking structure which is operable between a first position and a second position, and wherein
the blocking structure in the first position prevents axial movement of the release element and in the second position allows axial movement of the release element,
and which blocking structure is operational by the rotatable display element,
such that whenever the rotatable display element is rotated to a specific axial position and/or rotational position it activates the blocking structure such that the release element becomes axially movable to thereby release the set dose.

### Claim 2 (depends on 1)

The torsion spring driven injection device according to claim 1, wherein the rotatable display element is coupled to the dose setting structure such that the rotatable display element follows rotation of the dose setting structure.

### Claim 3 (depends on 2)

The torsion spring driven injection device according to claim 2, wherein the dose setting structure comprises a ratchet tube having the rotatable display element coupled thereto.

### Claim 4 (depends on 1)

The torsion spring driven injection device according to claim 1, wherein the rotatable display element is guided relatively to the housing structure by a helical interface such that the rotatable display element moves helically when rotated.

### Claim 5 (depends on 1)

The torsion spring driven injection device according to claim 1, wherein a ratchet tube and the release element are coupled to each other such that the release element follows axial movement of the ratchet tube.

### Claim 6 (depends on 1)

The torsion spring driven injection device according to claim 1, wherein a ratchet tube is coupled to follow axial movement of a reset tube comprised in the dose setting structure.

### Claim 7 (depends on 1)

The torsion spring driven injection device according to claim 1, wherein the release element is axially movable in the distal direction into engagement with the rotatable drive element by axial movement of the dose setting structure during dosing.

### Claim 8 (depends on 1)

The torsion spring driven injection device according to claim 1, wherein the dose setting structure is provided with one or more locking arms engaging the housing structure to thereby prevent axial movement of the dose setting structure.

### Claim 9 (depends on 8)

The torsion spring driven injection device according to claim 8, wherein the rotatable display element activates the locking arm to move out of engagement with the housing structure at a specific position of the rotatable display element relatively to the housing structure.

### Claim 10 (depends on 9)

The torsion spring driven injection device according to claim 9, wherein the housing structure on the inner surface is provided with a flange structure engaging the locking arm to prevent axial movement of the ratchet tube and wherein, the rotatable display element moves the locking arm away from the flange structure at a specific position of the rotatable display element relatively to the housing structure.

### Claim 11 (depends on 1)

The torsion spring driven injection device according to claim 1, wherein coupling between the ratchet tube and the rotatable display element is by groove and tongue engagement.

### Claim 12

A torsion spring driven injection device for ejecting at least one dose of a liquid drug comprising:
a housing structure securing a container containing the liquid drug to be ejected,
a rotational dose setting element operable by a user for setting the size of the dose to be ejected,
a rotatable dose setting structure transferring rotation from the dose setting element to a straining of a torsion spring such that a torque is stored in the torsion spring upon rotation of the dose setting element,
a rotatable display element arranged to follow rotation of the dose setting structure and helically movable relatively to the housing structure from an initial position to a dosing position, wherein the set dose is indicated by the rotatable dose setting element,
a piston rod arranged in a longitudinal direction and movable in a distal direction to expel the set dose out from the container,
a rotatable drive element engaging the piston rod and adapted to move the piston rod in the distal direction upon rotation of the rotatable drive element,
an axially movable release element for releasing the torque stored in the torsion spring to rotate the rotatable drive element,
wherein the release element is provided with one or more teeth axially engaging corresponding teeth provided on the rotatable drive element and a torque arising from the torsion spring during dosing is transferred from the one or more teeth of the release element to the corresponding teeth on the rotatable drive element such that a rotation of the release element during dosing is transferred to a rotation of the rotatable drive element,
and wherein the one or more teeth on the release element are slidable in the axial direction in relation to the corresponding teeth on the rotatable drive element,
wherein,
at least one of the corresponding teeth on the rotatable drive element proximally is provided with a radial extension which hinders the teeth and the release element from sliding in the axial direction in relation to the corresponding teeth on the rotatable drive element when a torque above a certain threshold value is being applied to the corresponding teeth.

### Claim 13 (depends on 12)

The torsion spring driven injection device according to claim 12, wherein the transformation between the corresponding teeth and the radial extension comprises a sloped surface along which the one or more teeth can slide when no torque is applied to the corresponding teeth.

### Claim 14 (depends on 12)

The torsion spring driven injection device according to claim 12, wherein the radial extension is shaped such that it permanently locks the teeth and the release element from axial movement.

### Claim 15 (depends on 12)

The torsion spring drive injection device according to claim 12, wherein between the teeth and the radial extension comprises a sloped surface along which the one or more teeth can slide when no torque is applied to the corresponding teeth.

### Claim 16 (depends on 12)

The torsion spring drive injection device according to claim 12, wherein the radial extension is shaped such that it locks the teeth and the release element from axial movement.

### Claim 17 (depends on 12)

The torsion spring driven injection device according to claim 12, wherein the release element is on an outer surface.