# US 12,109,354 B2 · Negative-pressure therapy with adjustable instillation pump chamber > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,109,354 B2 - Document ID: US12109354B2 - Status: Granted - Kind: B2 - Application number: 17/220,706 - Filed: 2021-04-01 - Published: 2021-07-22 - Granted: 2024-10-08 - Earliest claimed: 2017-07-18 - Assignees: Solventum Intellectual Properties Company - Applicants: Solventum Intellectual Properties Company - Inventors: Benjamin Andrew Pratt; Christopher Brian Locke - Web page: https://patentgrep.com/patent/US12109354B2 ## CPC - A61M 1/92: {with liquid supply means} - A61M 1/784: {by filtering, sterilising or disinfecting the exhaust air, e.g. swellable filter valves} - A61M 1/85: {with gas or fluid supply means, e.g. for supplying rinsing fluids or anticoagulants (for negative pressure wound therapy A61M1/92, A61M1/94; combined with tracheal tubes A61M16/0463; dental instruments with combined rinsing and aspirating A61C17/0208)} - A61M 3/0208: {before use} - A61M 3/022: {Volume; Flow rate} - A61M 3/0283: {with at least two inner passageways, a first one for irrigating and a second for evacuating (suction-irrigation systems A61M1/77; aspiration tips with fluid supply means A61M1/85; for negative pressure wound therapy A61M1/92)} - A61M 27/00: Drainage appliance for wounds or the like {, i.e. wound drains, implanted drains} ({negative pressure wound therapy devices A61M1/90;} implements for holding wound open A61B17/02 {; middle ear drainage A61F11/202}) - A61M 1/78: {Means for preventing overflow or contamination of the pumping systems (combined with drainage containers A61M1/60)} - A61M 3/0202: {with electronic control means or interfaces} - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract Systems, apparatuses, and methods for instilling fluid to a tissue site in a negative-pressure therapy environment are described. Illustrative embodiments may include a pneumatically-actuated instillation pump that can draw a solution from a solution source during a negative-pressure interval, and instill the solution to a dressing during a venting interval. A pneumatic actuator may be mechanically coupled to a disposable distribution system that can provide a fluid path between the solution source and a distribution component. A bacterial filter may be disposed in the fluid path between the actuator and the distribution component to prevent contamination of the actuator during operation. The distribution system may be separated from the actuator and disposed of after operation, and the actuator may be re-used. ## Claims ### Claim 1 A system for providing negative-pressure and instillation therapy, the system comprising: a negative-pressure source configured to provide negative pressure; a controller electrically coupled to the negative-pressure source and configured to turn on the negative-pressure source during a negative-pressure interval and turn off the negative-pressure source during a venting interval; an actuator comprising a dosing piston and a priming piston configured to be coupled to the negative-pressure source; and a distribution system comprising a dosing chamber, a priming chamber fluidly coupled to the dosing chamber, a fluid port configured to be fluidly coupled to the dosing chamber and to the negative-pressure source, and a fluid fitting configured to couple the dosing piston and the priming piston to the fluid port; wherein the actuator is configured further to open the priming chamber and expand the dosing chamber during the negative-pressure interval, and close the priming chamber and contract the dosing chamber during the venting interval. ### Claim 2 (depends on 1) The system of claim 1, wherein the distribution system comprises a bacterial filter between the fluid port and the fluid fitting. ### Claim 3 (depends on 1) The system of claim 1, further comprising a solution source fluidly coupled to the priming chamber. ### Claim 4 (depends on 1) The system of claim 1, wherein the distribution system further comprises: a first check valve fluidly coupled to the priming chamber and a solution source; and a second check valve fluidly coupled to the dosing chamber and to the fluid port. ### Claim 5 (depends on 1) The system of claim 1, wherein the distribution system further comprises: a first fluid conductor between the dosing chamber and the fluid port; and a second fluid conductor between the fluid fitting and the fluid port. ### Claim 6 (depends on 1) The system of claim 1, wherein the priming chamber comprises a rolling diaphragm. ### Claim 7 (depends on 1) The system of claim 1, wherein the dosing chamber comprises a rolling diaphragm. ### Claim 8 (depends on 1) The system of claim 1 wherein the actuator further comprises an ambient piston configured to be coupled to the negative-pressure source. ### Claim 9 (depends on 1) The system of claim 1, wherein the distribution system further comprises a control valve fluidly coupled between the dosing chamber and the fluid port. ### Claim 10 A system for providing negative-pressure and instillation to a tissue site, the system comprising: a negative-pressure device comprising a negative-pressure source and a controller electrically coupled to the negative-pressure source, the controller configured to turn on the negative-pressure source during a negative-pressure interval and turn off the negative-pressure source during a venting interval; an instillation device comprising a dosing valve having a working chamber and a dosing chamber configured to be fluidly coupled to a fluid port, a priming valve having a working chamber and a priming chamber fluidly coupled to the dosing chamber and configured to be fluidly coupled to a source of fluids, the working chambers configured to be fluidly coupled to the negative-pressure source; and a canister configured to be coupled to the instillation device and fluidly coupled through the instillation device between the negative-pressure source and the fluid port for collecting fluids. ### Claim 11 (depends on 10) The system of claim 10, wherein the working chambers further comprise actuators configured to open the priming chamber to expand the dosing chamber during the negative-pressure interval, and close the priming chamber to contract the dosing chamber during the venting interval. ### Claim 12 (depends on 10) The system of claim 10, wherein the negative-pressure device is configured to be coupled to the instillation device. ### Claim 13 (depends on 10) The system of claim 10, wherein the negative-pressure device is configured to be coupled interchangeably to the instillation device and the canister. ### Claim 14 (depends on 10) The system of claim 10, wherein the instillation device is configured to be coupled between the negative-pressure device and the canister, wherein the negative-pressure device is fluidly coupled through the instillation device to the canister.