# US 12,109,335 B2 · Composition for acoustic wave probe, silicone resin for acoustic wave probe, acoustic wave probe, ultrasound probe, acoustic wave measurement apparatus, ultrasound diagnostic apparatus, photoacoustic wave measurement apparatus, and ultrasound endoscope > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,109,335 B2 - Document ID: US12109335B2 - Status: Granted - Kind: B2 - Application number: 16/811,636 - Filed: 2020-03-06 - Published: 2020-07-02 - Granted: 2024-10-08 - Earliest claimed: 2017-09-11 - Assignees: FUJIFILM Corporation; Shin-Etsu Chemical Co., Ltd. - Applicants: FUJIFILM Corporation; Shin-Etsu Chemical Co., Ltd. - Inventors: Yoshihiro Nakai; Shigeki Uehira; Taichi Kitagawa; Nobuaki Matsumoto - Web page: https://patentgrep.com/patent/US12109335B2 ## CPC - A61L 31/129: {containing macromolecular fillers} - A61B 5/0095: {by applying light and detecting acoustic waves, i.e. photoacoustic measurements} - A61B 8/12: in body cavities or body tracts, e.g. by using catheters - A61B 8/4281: {characterised by sound-transmitting media or devices for coupling the transducer to the tissue} - A61B 8/4444: {related to the probe} - A61L 31/028: {Other inorganic materials not covered by A61L31/022 - A61L31/026} - A61L 31/06: obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds {(A61L31/041 takes precedence)} - A61L 31/128: {containing other specific inorganic fillers not covered by A61L31/126 or A61L31/127} - A61L 31/14: Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials} - C08G 77/70: {Siloxanes defined by use of the MDTQ nomenclature} - C08K 9/06: with silicon-containing compounds - C08L 83/04: Polysiloxanes - G01S 15/8906: {Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques} - G10K 11/30: using refraction, e.g. acoustic lenses - H04R 17/00: Piezoelectric transducers; Electrostrictive transducers (piezoelectric or electrostrictive elements in general H10N30/00; details of piezoelectric or electrostrictive motors, generators or positioners {H10N30/00}) - C08G 77/12: containing silicon bound to hydrogen - C08G 77/20: containing silicon bound to unsaturated aliphatic groups - C08K 3/36: Silica - C08L 2205/025: containing two or more polymers of the same hierarchy C08L, and differing only in parameters such as density, comonomer content, molecular weight, structure - C08L 2205/03: containing three or more polymers in a blend - G01S 7/52079: {Constructional features (constructional features of transducers B06B; mounting transducers G10K11/00; constructional features of ultrasonic medical diagnostic devices A61B8/44)} - G01S 15/8915: {using a transducer array} - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - C08G: MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS - C08K: Use of inorganic or non-macromolecular organic substances as compounding ingredients (paints, inks, varnishes, dyes, polishes, adhesives C09) - C08L: COMPOSITIONS OF MACROMOLECULAR COMPOUNDS (compositions based on polymerisable monomers C08F, C08G; artificial filaments or fibres D01F; textile treating compositions D06) - G01S: RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES - G10K: SOUND-PRODUCING DEVICES; METHODS OR DEVICES FOR PROTECTING AGAINST, OR FOR DAMPING, NOISE OR OTHER ACOUSTIC WAVES IN GENERAL; ACOUSTICS NOT OTHERWISE PROVIDED FOR - H04R: LOUDSPEAKERS, MICROPHONES, GRAMOPHONE PICK-UPS OR LIKE ACOUSTIC ELECTROMECHANICAL TRANSDUCERS; ELECTRIC HEARING AIDS; PUBLIC ADDRESS SYSTEMS (producing sounds with frequency not determined by supply frequency G10K) ## Abstract A composition for an acoustic wave probe, containing the following ingredients (A) to (D): (A) a linear polysiloxane having a vinyl group; (B) a linear polysiloxane having two or more Si—H groups in a molecular chain; (C) a polysiloxane resin; and (D) surface-treated silica particles having an average primary particle diameter more than 16 nm and less than 100 nm, as well as, a silicone resin for an acoustic wave probe, an acoustic wave probe, an ultrasound probe, an acoustic wave measurement apparatus, an ultrasound diagnostic apparatus, a photoacoustic wave measurement apparatus, and an ultrasound endoscope, using the composition for an acoustic wave probe. ## Claims ### Claim 1 A composition for an acoustic wave probe, comprising the following ingredients (A) to (D): (A) a linear polysiloxane having a vinyl group; (B) a linear polysiloxane having two or more Si—H groups in a molecular chain; (C) a polysiloxane resin; and (D) surface-treated silica particles having an average primary particle diameter ranging from 50 nm to less than 100 nm, wherein the ingredient (D) has a truly spherical shape. ### Claim 2 (depends on 1) The composition for an acoustic wave probe according to claim 1, wherein, in 100 parts by mass of a total of each content of the ingredients (A) to (D), the content of the ingredient (D) is 25 to 70 parts by mass. ### Claim 3 (depends on 1) The composition for an acoustic wave probe according to claim 1, wherein, in 100 parts by mass in the total of each content of the ingredients (A) to (D), the content of the ingredient (A) is 20 to 80 parts by mass, the content of the ingredient (B) is 0.1 to 20 parts by mass, and the content of the ingredient (C) is 0.1 to 50 parts by mass. ### Claim 4 (depends on 1) The composition for an acoustic wave probe according to claim 1, wherein the ingredient (D) are silica particles subjected to surface treatment using a silane compound. ### Claim 5 (depends on 4) The composition for an acoustic wave probe according to claim 4, wherein the ingredient (D) are silica particles subjected to surface treatment using a trimethylsilylating agent. ### Claim 6 (depends on 1) The composition for an acoustic wave probe according to claim 1, wherein a methanol hydrophobicity of the ingredient (D) is 40 to 80 mass %. ### Claim 7 (depends on 1) The composition for an acoustic wave probe according to claim 1, wherein the ingredient (A) has a phenyl group. ### Claim 8 (depends on 1) The composition for an acoustic wave probe according to claim 1, wherein a mass average molecular weight of the ingredient (A) is 20,000 to 200,000. ### Claim 9 (depends on 8) The composition for an acoustic wave probe according to claim 8, wherein the mass average molecular weight is 40,000 to 150,000. ### Claim 10 (depends on 1) The composition for an acoustic wave probe according to claim 1, wherein the ingredient (C) is a polysiloxane resin contains a R3SiO1/2 unit and a SiO4/2 unit and has at least two vinyl groups in one molecule, wherein a molar ratio of the R3SiO1/2 unit to the SiO4/2 unit is 0.6 to 1.2, and wherein R represents a monovalent hydrocarbon group. ### Claim 11 (depends on 10) The composition for an acoustic wave probe according to claim 10, wherein the ingredient (C) is constituted by the R3SiO1/2 unit and the SiO4/2 unit. ### Claim 12 (depends on 1) The composition for an acoustic wave probe according to claim 1, comprising: 0.00001 to 0.01 parts by mass of platinum or a platinum compound with respect to 100 parts by mass of the total of each content of the ingredients (A) to (D). ### Claim 13 (depends on 1) A silicone resin for an acoustic wave probe which is obtained by curing the composition for an acoustic wave probe according to claim 1. ### Claim 14 (depends on 13) An acoustic wave probe, comprising at least one of an acoustic lens containing the silicone resin for an acoustic wave probe according to claim 13 and an acoustic matching layer containing the silicone resin for an acoustic wave probe according to claim 13. ### Claim 15 (depends on 13) An ultrasound probe, comprising: a capacitive micromachined ultrasonic transducer as an ultrasonic transducer array; and an acoustic lens containing the silicone resin for an acoustic wave probe according to claim 13. ### Claim 16 (depends on 14) An acoustic wave measurement apparatus, comprising: the acoustic wave probe according to claim 14. ### Claim 17 (depends on 14) An ultrasound diagnostic apparatus, comprising: the acoustic wave probe according to claim 14. ### Claim 18 (depends on 13) A photoacoustic wave measurement apparatus, comprising: an acoustic lens containing the silicone resin for an acoustic wave probe according to claim 13. ### Claim 19 (depends on 13) An ultrasound endoscope, comprising: an acoustic lens containing the silicone resin for an acoustic wave probe according to claim 13.