# US 12,109,319 B2 · Rubber-based soft gel skin adhesives > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,109,319 B2 - Document ID: US12109319B2 - Status: Granted - Kind: B2 - Application number: 18/064,396 - Filed: 2022-12-12 - Published: 2023-04-13 - Granted: 2024-10-08 - Earliest claimed: 2016-11-11 - Assignees: Avery Dennison Corporation - Applicants: Avery Dennison Corporation - Inventors: Xianbo Hu; Neal Carty - Web page: https://patentgrep.com/patent/US12109319B2 ## CPC - A61L 15/585: {Mixtures of macromolecular compounds} - A61L 15/44: Medicaments - A61L 15/46: Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria - A61L 24/0015: {Medicaments; Biocides} - A61L 24/043: {Mixtures of macromolecular materials} - C08K 5/01: Hydrocarbons {(C08K5/0091 takes precedence)} - C08K 5/103: with polyalcohols - C08K 5/29: Compounds containing {one or more} carbon-to-nitrogen double bonds - C09J 125/10: with conjugated dienes - A61L 2300/206: Biguanides, e.g. chlorohexidine - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - C08K: Use of inorganic or non-macromolecular organic substances as compounding ingredients (paints, inks, varnishes, dyes, polishes, adhesives C09) - C09J: ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES (preparation of glue or gelatine C09H) ## Abstract Adhesives comprising rubber, tackifier, oil, and optionally absorbent and active ingredient are described. The adhesives are suitable for medical applications as they are repositionable on skin. Also described are medical articles using the adhesives. ## Claims ### Claim 1 An adhesive assembly comprising: a medical article having an exterior surface; and a region of adhesive disposed on the exterior surface of the medical article, the adhesive comprises: from about 7% to 33% of at least one rubber component, from about 15% to 45% of at least one tackifier, from about 15% to 60% of at least one mineral oil, from about 30% to 40% of at least one absorbent, at least one additive selected from the group consisting of a natural clay, a synthetic clay, micro fibers, nano fibers, fibrils of fibers, an antioxidant, a stabilizer, and combinations thereof, and optionally, at least one active ingredient, and wherein the adhesive exhibits a soft, gel-like consistency and is repositionable on skin; wherein the ratio of the amount of the tackifier to the amount of the rubber component ranges from 1:1 to 2.4:1; and wherein the ratio of the amount of the oil to the amount of the rubber component ranges from 1.3:1 to 2.6:1. ### Claim 2 (depends on 1) The adhesive assembly of claim 1 wherein the medical article is selected from the group comprising wound dressings, surgical dressings, medical tapes, athletic tapes, surgical tapes, sensors, electrodes, ostomy appliances or related components such as sealing rings, catheters, connector fittings, catheter hubs, catheter adapters, fluid delivery tubes, electrical wires and cables, negative pressure wound therapy (NPWT) components, surgical drains, wound draining components, IV site dressings, prostheses, stoma pouches, buccal patches, transdermal patches, dentures, hairpieces, bandages, diapers, medical padding for example liposuction padding, hygiene pads, corn and callous pads, pads for cushioning and protecting blisters, toe cushioning pads, and pads for protecting and cushioning tube sites such as tracheotomy tubes. ### Claim 3 (depends on 1) The adhesive assembly of claim 1 wherein at least one absorbent includes carboxymethyl cellulose. ### Claim 4 (depends on 1) The adhesive assembly of claim 1 wherein at least one active ingredient is chlorhexidine gluconate (CHG). ### Claim 5 (depends on 1) The adhesive assembly of claim 1 wherein at least one rubber component is at least one polymer selected from the group consisting of linear or radial A-B-A block copolymer, of linear or radial A-B block copolymer, branched block copolymer, and combinations thereof. ### Claim 6 (depends on 1) The adhesive assembly of claim 1 wherein at least one tackifier includes a hydrogenated pentaerythritol rosin ester, at least one hydrogenated hydrocarbon resin, and a styrenated terpene resin. ### Claim 7 (depends on 1) The adhesive assembly of claim 1 wherein at least one mineral oil includes a liquid polymer selected from the group comprising liquid isoprene rubber, liquid butadiene rubber, liquid polyisobutylene (PIB) and combinations thereof. ### Claim 8 (depends on 1) The adhesive assembly of claim 1 wherein the adhesive exhibits a fluid handling capacity (FHC) within a range of about 50 grams/m2/day to about 5,000 grams/m2/day. ### Claim 9 (depends on 1) The adhesive of claim 1 wherein the adhesive exhibits a storage modulus (G′) at a temperature of about 22° C. to about 37° C. and a frequency of about 0.01 rad/s of about 100 Pa to about 30,000 Pa. ### Claim 10 (depends on 1) The adhesive of claim 1 wherein the adhesive exhibits a storage modulus (G′) at a temperature of about 22° C. to about 37° C. and a frequency of about 100 rad/s of about 5,000 Pa to about 150,000 Pa. ### Claim 11 (depends on 1) The adhesive of claim 1 wherein the adhesive exhibits a loss modulus (G″) at a temperature of about 22° C. to about 37° C. and a frequency of about 0.01 rad/s of about 100 Pa to about 10,000 Pa. ### Claim 12 (depends on 1) The adhesive of claim 1 wherein the adhesive exhibits a loss modulus (G″) at a temperature of about 22° C. to about 37° C. and a frequency of about 100 rad/s of about 1,000 Pa to about 30,000 Pa. ### Claim 13 (depends on 1) The adhesive of claim 1 wherein the adhesive has a glass transition temperature within a range from about −70° C. to about 0° C.