# US 12,109,314 B2 · Soft capsule film composition

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 12,109,314 B2
- Document ID: US12109314B2
- Status: Granted
- Kind: B2
- Application number: 17/049,095
- Filed: 2019-04-24
- Published: 2021-07-01
- Granted: 2024-10-08
- Earliest claimed: 2018-04-26
- Assignees: Fuji Capsule Co., Ltd.
- Applicants: Fuji Capsule Co., Ltd.
- Inventors: Yuki Obatake; Yosuke Kondo; Koji Masuda; Kazuhiko Watanabe; Yoshihiko Watanabe
- Web page: https://patentgrep.com/patent/US12109314B2

## CPC

- A61K 9/4816: {Wall or shell material}
- A61K 47/36: Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)

## Abstract

A soft capsule film composition, comprising: (A) a native gellan gum; (B) one or more hydrophilic polysaccharides; (C) a starch or modified starch; (D) a plasticizer; and (E) water, wherein a gelling agent other than the native gellan gum and the one or more hydrophilic polysaccharides is not an essential component. The soft capsule film composition shortens drying time at room temperature, suppresses the stickiness of the surface of a film sheet, imparts film sheet strength which can withstand continuous production in factory manufacturing with a rotary die filling machine or the like, and enables the manufacture of a good soft capsule with high adhesiveness. For this reason, the soft capsule produced using the soft capsule film composition can be utilized for various uses such as drugs, quasi drugs, cosmetics, and foods.

## Claims

### Claim 1

A soft capsule film composition, comprising: (A) a native gellan gum; (B) one or more hydrophilic polysaccharides selected from low methoxy pectin, locust bean gum and xanthan gum; (C) a starch dispersion formed by subjecting a starch glue solution prepared from an unmodified starch to ultrasonic treatment; (D) a plasticizer; and (E) water, wherein the composition does not comprise a gelling agent other than (A) the native gellan gum and (B) the one or more hydrophilic polysaccharides selected from low methoxy pectin, locust bean gum and xanthan gum, wherein a content mass ratio of (A) the native gellan gum to (C) the starch dispersion formed by subjecting a starch glue solution prepared from an unmodified starch to ultrasonic treatment [(A):(C)] is 1:5.5 to 1:8.5.

### Claim 2 (depends on 1)

The soft capsule film composition according to claim 1, further comprising a starch subjected to moist heat treatment in the presence of a salt.

### Claim 3 (depends on 1)

The soft capsule film composition according to claim 1, further comprising waxy potato starch.

### Claim 4 (depends on 1)

The soft capsule film composition according to claim 1, wherein a content mass ratio of (A) the native gellan gum to (B) the one or more hydrophilic polysaccharides selected from low methoxy pectin, locust bean gum and xanthan gum [(A):(B)] is 1:1 to 1:0.01.

### Claim 5 (depends on 1)

The soft capsule film composition according to claim 1, wherein the starch dispersion formed by subjecting a starch glue solution prepared from an unmodified starch to ultrasonic treatment is a starch dispersion derived from waxy corn starch.

### Claim 6 (depends on 5)

The soft capsule film composition according to claim 5, wherein the waxy corn starch used for the starch dispersion formed by subjecting a starch glue solution prepared from an unmodified starch to ultrasonic treatment is an unmodified natural starch.

### Claim 7 (depends on 2)

The soft capsule film composition according to claim 2, wherein the starch subjected to moist heat treatment in the presence of a salt is waxy corn starch subjected to moist heat treatment in the presence of a salt.

### Claim 8 (depends on 1)

A soft capsule film, wherein the soft capsule film is obtained using the soft capsule film composition according to claim 1.

### Claim 9 (depends on 1)

A soft capsule, wherein the soft capsule is obtained using the soft capsule film composition according to claim 1.