# US 12,109,299 B2 · Plant lipid composition for promoting hair growth, method for promoting hair growth and use of said plant lipids

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- Number: US 12,109,299 B2
- Document ID: US12109299B2
- Status: Granted
- Kind: B2
- Application number: 17/354,400
- Filed: 2021-06-22
- Published: 2021-10-14
- Granted: 2024-10-08
- Earliest claimed: 2015-12-28
- Assignees: Natura Cosmeticos S.A.
- Applicants: Natura Cosméticos S.A.
- Inventors: Juliana Carvalhães Lago; Daniela Zimbardi; Carla Maria Sanches Scanavez De Paula; Ana Paula Pedroso De Oliveira; Cintia Rosa Ferrari; Caroline Ziegler Stüker; Juliana Beltrame Reigada; Debora Cristina Castellani
- Web page: https://patentgrep.com/patent/US12109299B2

## CPC

- A61K 8/922: {of vegetable origin}
- A61K 36/889: Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
- A61P 17/14: for baldness or alopecia
- A61Q 7/00: Preparations for affecting hair growth
- A61K 2800/91: Injection
- A61K 2800/92: Oral administration
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

Cosmetic and/or pharmaceutical compositions for promoting hair growth by modulating the expression of genes involved in the JAK-STAT signaling pathway are provided. The compositions include at least one plant lipid, preferably pataua (Oenocarpus bataua) oil. Also included are methods for promoting hair growth by modulating the expression of genes involved in the JAK-STAT signaling pathway.

## Claims

### Claim 1

A topical composition for promoting hair growth by modulating the expression of genes related to the JAK-STAT signaling pathway, said topical composition consisting essentially of pataua (Oenocarpus bataua) oil and a pharmaceutically and/or cosmetically acceptable carrier, wherein the pataua oil is present in an amount ranging from about 1% to about 5% by weight based on the total weight of the topical composition;
wherein the hair growth is promoted by modulating the expression of STAT3.

### Claim 2 (depends on 1)

The composition according to claim 1, wherein the composition is formulated as aqueous, alcoholic or oily solutions, dispersions, emulsions, suspensions, or aerosol compositions comprising a pressurized propellant agent.

### Claim 3 (depends on 1)

The composition according to claim 1, wherein the pharmaceutically and/or cosmetically acceptable carrier comprises one or more chelating agents, emulsifiers, moisturizers, sunscreens, emollients, consistency agents, thickeners and/or viscosity agents, sensory modifiers, antioxidants, oils and/or waxes, solvents, gelling agents, preservative agents, pH correction agents, conditioning agents, surfactants, pearlizing agents, deodorants, or any combination thereof.