Method for isolating and detecting cancer stem cells
AssigneeSylvain Gnaho
InventorsVincent Carre, Aurélie Lacroix
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Abstract
Disclosed is the in vitro use of at least one lectin for marking cancer stem cells of hormone-dependent cancer target organs, selected from the lectins Maackia amurensis lectin II (MAH-II), Euonymus europaeus lectin (EEL), Psophocarpus tetragonolobus lectin I (PTL-I) and Griffonia simplicifolia lectin II (GSL-II), in particular at least two lectins selected from MAH-II, EEL, PTL-I and GSL-II, in particular the two lectins MAH-II and EEL, in order to obtain cancer stem cells of labeled hormone-dependent cancer target organs in a biological sample.
Claims6
An in vitro method of detecting cancer stem cells of hormone-dependent cancer target organs, the method comprising contacting a biological sample with at least two labeled lectins, wherein the lectins are Maackia amurensis lectin II (MAH-II), and Euonymus europaeus lectin (EEL), and thereby labeling and detecting cancer stem cells from an organ of hormone-dependent cancer, wherein the at least two lectins are in equal amount or in a 2:1 ratio by weight, and wherein the organ is breast, uterus, or ovaries.
Dependencies are inferred from the claim text.