Anti-migration micropatterned stent coating

An endoprosthesis comprising:

• a stent having an inner surface defining a lumen, an outer surface, wherein the stent defines a plurality of apertures extending between the outer surface and the lumen;
• and
• a polymeric coating attached to the outer surface of the stent and covering at least some of the plurality of apertures, the polymeric coating including a first surface attached to the outer surface of the stent, and a second surface facing outwardly from the stent, the polymeric coating defining a tissue engagement portion including a plurality of openings in the second surface from which a first plurality of holes extend toward the first surface, the tissue engagement portion including a plurality of interwinding fibers defining a second plurality of holes positioned below the second surface and in fluid communication with at least one of the first plurality of holes forming an interconnected network of holes;
• wherein the polymeric coating further comprises a plurality of micropillars extending outwardly from the second surface, away from the first surface;
• wherein the first plurality of holes are configured to allow tissue ingrowth into the second surface of the polymeric coating and the second plurality of holes are configured to allow tissue ingrowth within the tissue engagement portion upon initial implantation of the endoprosthesis in a body lumen.

An endoprosthesis comprising:

• a stent having an inner surface defining a lumen, an outer surface, wherein the stent defines a plurality of apertures extending between the outer surface and the lumen;
• and
• a polymeric coating attached to the outer surface of the stent and covering at least some of the plurality of apertures, the polymeric coating including a first surface attached to the outer surface of the stent, and a second surface facing radially outwardly from the stent, the polymeric coating defining a tissue engagement portion including a plurality of openings in the second surface from which a first plurality of holes extend toward the first surface, the tissue engagement portion defining a second plurality of holes positioned below the second surface and in fluid communication with at least one of the first plurality of holes forming an interconnected network of holes;
• wherein the polymeric coating further comprises a plurality of spaced apart micropillars extending radially outwardly from the second surface, away from the first surface, wherein the plurality of openings in the second surface are disposed between micropillars;
• wherein the first plurality of holes are configured to allow tissue ingrowth into the second surface of the polymeric coating and the second plurality of holes are configured to allow tissue ingrowth within the tissue engagement portion upon initial implantation of the endoprosthesis in a body lumen.