# US 12,108,964 B2 · Minimally invasive tissue treatment device > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,108,964 B2 - Document ID: US12108964B2 - Status: Granted - Kind: B2 - Application number: 18/048,296 - Filed: 2022-10-20 - Published: 2023-03-02 - Granted: 2024-10-08 - Earliest claimed: 2007-01-02 - Assignees: AquaBeam, LLC - Applicants: AquaBeam, LLC - Inventors: Nikolai Aljuri; Rodney C. Perkins - Web page: https://patentgrep.com/patent/US12108964B2 ## CPC - A61B 17/3203: Fluid jet cutting instruments - A61B 17/32037: {for removing obstructions from inner organs or blood vessels, e.g. for atherectomy} - A61B 18/04: by heating (by applying electromagnetic radiation A61B18/18) - A61B 18/14: Probes or electrodes therefor - A61B 18/1485: {having a short rigid shaft for accessing the inner body through natural openings} - A61B 18/1492: {having a flexible, catheter-like structure, e.g. for heart ablation (A61B18/1477 takes precedence)} - A61B 18/18: by applying electromagnetic radiation, e.g. microwaves - A61B 18/201: {with beam delivery through a hollow tube, e.g. forming an articulated arm (through a flexible conduit A61B18/22); Hand-pieces therefor} - A61B 18/24: with a catheter (A61B18/26, A61B18/28 take precedence) - A61F 9/007: Methods or devices for eye surgery - A61F 9/00736: {Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments (A61F9/008 takes precedence)} - A61B 2017/00274: {Prostate operation, e.g. prostatectomy, turp, bhp treatment} - A61B 2017/00292: {mounted on or guided by flexible, e.g. catheter-like, means} - A61B 2017/22069: {Immobilising; Stabilising} - A61B 2017/22079: {with suction of debris} - A61B 2018/00017: {with gas} - A61B 2018/00196: {reciprocating lengthwise} - A61B 2018/00202: {rotating} - A61B 2018/00285: {Balloons} - A61B 2018/00547: {Prostate} - A61B 2018/00577: {Ablation} - A61B 2018/00583: {Coblation, i.e. ablation using a cold plasma} - A61B 2018/00595: {Cauterization} - A61B 2018/00601: {Cutting} - A61B 2018/00946: {slidable} - A61B 2018/00952: {rotatable} - A61B 2018/00982: {combined with or comprising means for visual or photographic inspections inside the body, e.g. endoscopes} - A61B 2018/046: {in liquid form} - A61B 2018/144: {Wire} - A61B 2018/1472: {for use with liquid electrolyte, e.g. virtual electrodes} - A61B 2018/1497: {Electrodes covering only part of the probe circumference} - A61B 2018/1861: {with an instrument inserted into a body lumen or cavity, e.g. a catheter} - A61B 2018/20351: {Scanning mechanisms} - A61B 2018/2277: {with refractive surfaces} - A61B 2090/064: {for measuring force, pressure or mechanical tension} - A61B 2217/005: with suction drainage system - A61B 2218/002: Irrigation - A61B 2218/007: Aspiration - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) ## Abstract Prostate treatment using fluid stream to resect prostate tissue, thereby relieving symptoms of conditions such as BPH, prostatitis, and prostatic carcinoma. A device having a fluid delivery element is positioned within a lumen of the urethra within the prostate. A fluid stream is directed outwardly from the fluid delivery element toward a wall of the urethral lumen. The fluid delivery element is moved to scan the fluid stream over the wall to remove a volume of tissue surrounding the lumen. The fluid may be combined with therapeutically active substances or with substances that increase resection efficiency. Fluid force may be adjusted to provide selective tissue resection such that soft tissue is removed while harder tissue is left undamaged. In order to gain a working space within the urethra, another fluid may be introduced to insufflate the urethra in the region of treatment. ## Claims ### Claim 1 A tissue treatment device comprising: a shaft having a proximal end and a distal end; and an energy source positioned in an energy delivery region on the shaft configured to deliver an energy radially outwardly; wherein the energy source is adapted to be translated and rotated relative to the shaft to selectively direct the energy from the energy source to treat different regions of a tissue and wherein the tissue comprises a prostate tissue and the energy source is adapted to be placed in a urethra of a patient to treat the prostate tissue, wherein the energy source comprises an electrode and the electrode comprises a laterally projecting electrode configured to engage against tissue and deliver radio frequency energy to ablate the tissue; wherein the shaft has a width in a range from 1 mm to 10 mm and a length in a range from 15 cm to 25 cm. ### Claim 2 (depends on 1) The tissue treatment device of claim 1, further comprising a lumen in the shaft configured for one or more of insufflation, pressurization, aspiration, or flushing. ### Claim 3 (depends on 1) The tissue treatment device of claim 1, further comprising an expandable anchor near the distal end for anchoring in a bladder. ### Claim 4 (depends on 3) The tissue treatment device of claim 3, wherein the expandable anchor comprises a balloon adopted to expand to occupy an interior of the bladder when it is inflated. ### Claim 5 (depends on 1) The tissue treatment device of claim 1, wherein the energy source comprises a laser energy source. ### Claim 6 (depends on 5) The tissue treatment device of claim 5, wherein the energy source further comprises a mirror for reflecting laser energy. ### Claim 7 (depends on 1) The tissue treatment device of claim 1, wherein the energy source comprises a conductive fluid source and a radiofrequency energy source. ### Claim 8 (depends on 1) The tissue treatment device of claim 1, wherein the energy source comprises one or more of a laser energy source, a radiofrequency energy source, a thermal energy source, a mechanical energy source, a vibrational energy source, or a cooling energy source. ### Claim 9 (depends on 8) The tissue treatment device of claim 8, wherein the energy source comprises the thermal energy source. ### Claim 10 (depends on 8) The tissue treatment device of claim 8, wherein the energy source comprises a plurality of energy sources. ### Claim 11 A tissue treatment device comprising: a shaft having a proximal end and a distal end; and an energy source positioned in an energy delivery region on the shaft configured to deliver an energy radially outwardly; wherein the energy source is adapted to be translated and rotated relative to the shaft to selectively direct the energy from the energy source to treat different regions of a tissue and wherein the tissue comprises a prostate tissue and the energy source is adapted to be placed in a urethra of a patient to treat the prostate tissue and wherein the energy source comprises an electrode and the electrode projects laterally from a tube; wherein the shaft has a width in a range from 1 mm to 10 mm and a length in a range from 15 cm to 25 cm. ### Claim 12 A tissue treatment device comprising: a shaft having a proximal end and a distal end; and an energy source positioned in an energy delivery region on the shaft configured to deliver an energy radially outwardly; wherein the energy source is adapted to be translated and rotated relative to the shaft to selectively direct the energy from the energy source to treat different regions of a tissue and wherein the tissue comprises a prostate tissue and the energy source is adapted to be placed in a urethra of a patient to treat the prostate tissue and wherein the energy source comprises an electrode and the electrode is configured to ablate tissue and to cauterize tissue after ablation by changing a radiofrequency energy; wherein the shaft has a width in a range from 1 mm to 10 mm and a length in a range from 15 cm to 25 cm. ### Claim 13 A tissue treatment device comprising: a shaft having a proximal end and a distal end; and an energy source positioned in an energy delivery region on the shaft configured to deliver an energy radially outwardly; wherein the energy source is adapted to be translated and rotated relative to the shaft to selectively direct the energy from the energy source to treat different regions of a tissue and wherein the tissue comprises a prostate tissue and the energy source is adapted to be placed in a urethra of a patient to treat the prostate tissue and wherein the energy source comprises an electrode and the electrode is configured to deliver electrical energy in either a monopolar or bipolar mode; wherein the shaft has a width in a range from 1 mm to 10 mm and a length in a range from 15 cm to 25 cm.